当我在Visual Studio中遇到这个错误时，

"在建立与SQL Server的连接时，发生了与网络相关或特定于实例的错误。未找到服务器或无法访问服务器。验证实例名称是否正确，SQL Server是否配置为允许远程连接。(提供商:命名管道提供商，错误:40 -无法打开到SQL Server的连接)"

.．.它是在执行下面的c#代码期间，它试图获取我的SQL Server数据以在网格中显示。中断恰好发生在表示connect.Open()的行上:

        using (var connect = Connections.mySqlConnection)
        {
            const string query = "SELECT Name, Birthdate, Narrative FROM Friends";
            using (var command = new SqlCommand(query, connect))
            {
                connect.Open();
                using (var dr = command.ExecuteReader())
                {
                    while (dr.Read())
                    {
                        // blah
                    }
                }
            }
        }

It was inexplicable because the SQL query was very simple, I had the right connection string, and the database server was available. I decided to run the actual SQL query manually myself in SQL Management Studio and it ran just fine and yielded several records. But one thing stood out in the query results: there was some improperly encoded HTML text inside a varchar(max) type field within the Friends table (specifically, some encoded comment symbols of the sort <!-- lodged within the "Narrative" column's data). The suspect data row looked like this:

Name    Birthdate    Narrative
====    =========    ============== 
Fred    21-Oct-79    <!--HTML Comment -->Once upon a time...

注意编码的HTML符号“&lt;”，它代表一个“<”字符。不知何故，它进入了数据库，而我的c#代码无法接收它!它每次都失败在connect.Open()行!在我手动编辑数据库表Friends中的一行数据并输入解码后的“<”字符之后，一切都正常了!这一行应该是这样的:

Name    Birthdate    Narrative
====    =========    ============== 
Fred    21-Oct-79    <!--HTML Comment -->Once upon a time...

我使用下面这个简单的UPDATE语句编辑了一个不好的行。但如果你有几行违规的HTML编码，你可能需要一个更详细的UPDATE语句，使用REPLACE函数:

UPDATE Friends SET Narrative = '<!--HTML Comment -->Once upon a time...' WHERE Narrative LIKE '&lt%'

因此，这个故事的寓意是(至少在我的情况下)，在将HTML内容存储到数据库之前清理它，这样您就不会在第一时间得到这个神秘的SQL Server错误!(如果你需要更多信息，正确地消毒/解码你的HTML内容是另一个值得单独在StackOverflow搜索的讨论主题!)

在尝试了所有的答案后，我把端口号(1433)放在服务器名后，用逗号插入连接字符串，为我工作。如下所示:

"Server=**.***.***.*\\MYSERVER,1433;Database=****;User Id=****;Password=*****;MultipleActiveResultSets=true;TrustServerCertificate=True"

除了尝试Teo Chuen Wei Bryan建议的所有方法外，还要确保在连接字符串中引用了正确的服务器/实例名称。

如果您在数据库服务器或web上使用主机名/实例的简写形式。配置文件，确保您使用完全限定域名(FQDN)/实例

此外，要从不存在SQL server客户端的服务器测试连通性，

——>创建一个文本文件，并将其扩展名为。udl

右键单击文件，你可以看到连接选项卡。

——>输入服务器名和登录信息，测试连接到数据库服务器。

希望这能有所帮助。

当我在Visual Studio中遇到这个错误时，

"在建立与SQL Server的连接时，发生了与网络相关或特定于实例的错误。未找到服务器或无法访问服务器。验证实例名称是否正确，SQL Server是否配置为允许远程连接。(提供商:命名管道提供商，错误:40 -无法打开到SQL Server的连接)"

.．.它是在执行下面的c#代码期间，它试图获取我的SQL Server数据以在网格中显示。中断恰好发生在表示connect.Open()的行上:

        using (var connect = Connections.mySqlConnection)
        {
            const string query = "SELECT Name, Birthdate, Narrative FROM Friends";
            using (var command = new SqlCommand(query, connect))
            {
                connect.Open();
                using (var dr = command.ExecuteReader())
                {
                    while (dr.Read())
                    {
                        // blah
                    }
                }
            }
        }

It was inexplicable because the SQL query was very simple, I had the right connection string, and the database server was available. I decided to run the actual SQL query manually myself in SQL Management Studio and it ran just fine and yielded several records. But one thing stood out in the query results: there was some improperly encoded HTML text inside a varchar(max) type field within the Friends table (specifically, some encoded comment symbols of the sort <!-- lodged within the "Narrative" column's data). The suspect data row looked like this:

Name    Birthdate    Narrative
====    =========    ============== 
Fred    21-Oct-79    <!--HTML Comment -->Once upon a time...

注意编码的HTML符号“&lt;”，它代表一个“<”字符。不知何故，它进入了数据库，而我的c#代码无法接收它!它每次都失败在connect.Open()行!在我手动编辑数据库表Friends中的一行数据并输入解码后的“<”字符之后，一切都正常了!这一行应该是这样的:

Name    Birthdate    Narrative
====    =========    ============== 
Fred    21-Oct-79    <!--HTML Comment -->Once upon a time...

我使用下面这个简单的UPDATE语句编辑了一个不好的行。但如果你有几行违规的HTML编码，你可能需要一个更详细的UPDATE语句，使用REPLACE函数:

UPDATE Friends SET Narrative = '<!--HTML Comment -->Once upon a time...' WHERE Narrative LIKE '&lt%'

因此，这个故事的寓意是(至少在我的情况下)，在将HTML内容存储到数据库之前清理它，这样您就不会在第一时间得到这个神秘的SQL Server错误!(如果你需要更多信息，正确地消毒/解码你的HTML内容是另一个值得单独在StackOverflow搜索的讨论主题!)

总结

要修复在运行本地应用程序与远程数据库时遇到的此问题，请使用SQL Server配置管理器为远程数据库添加别名。

细节

I had run into this problem recently when transitioning from a Windows 7 to a Windows 10 laptop. I was running a local development and runtime environment accessing our Dev database on a remote server. We access the Dev database through a server alias setup through SQL Server Client Network Utility (cliconfg.exe). After confirming that the alias was correctly setup in both the 64 and 32 bit versions of the utility and that the database server was accessible from the new laptop via SSMS, I still got the error seen by the OP (not the OP's IP address, of course).

有必要使用SQL Server Configuration Manager为远程Dev数据库服务器添加别名。把事情都解决了。

我使用的是SQL Server 2016和windows 10。

首先是允许远程连接到SQL Server。 我所做的就是键入sqlservermanager13。在开始菜单打开SQL Server配置管理器。确保TCP/IP状态为启用状态。

双击TCP/IP协议名称，检查TCP端口号。通常默认值是1433。

以下步骤通过使用Microsoft管理控制台(MMC)管理单元配置Windows防火墙的高级安全。高级安全Windows防火墙只配置当前配置文件。

To open a port in the Windows firewall for TCP access On the Start menu, click Run, type WF.msc, and then click OK. In the Windows Firewall with Advanced Security, in the left pane, right-click Inbound Rules, and then click New Rule in the action pane. In the Rule Type dialog box, select Port, and then click Next. In the Protocol and Ports dialog box, select TCP. Select Specific local ports, and then type the port number of the instance of the Database Engine, such as 1433 for the default instance. Click Next. In the Action dialog box, select Allow the connection, and then click Next. In the Profile dialog box, select any profiles that describe the computer connection environment when you want to connect to the Database Engine, and then click Next. In the Name dialog box, type a name and description for this rule, and then click Finish.

另一个需要配置的东西。

To open access to SQL Server when using dynamic ports On the Start menu, click Run, type WF.msc, and then click OK. In the Windows Firewall with Advanced Security, in the left pane, right-click Inbound Rules, and then click New Rule in the action pane. In the Rule Type dialog box, select Program, and then click Next. In the Program dialog box, select This program path. Click Browse, and navigate to the instance of SQL Server that you want to access through the firewall, and then click Open. By default, SQL Server is at C:\Program Files\Microsoft SQL Server\MSSQL13.MSSQLSERVER\MSSQL\Binn\Sqlservr.exe. Click Next. In the Action dialog box, select Allow the connection, and then click Next. In the Profile dialog box, select any profiles that describe the computer connection environment when you want to connect to the Database Engine, and then click Next. In the Name dialog box, type a name and description for this rule, and then click Finish.

看看微软的文档 配置Windows防火墙访问数据库引擎