试试下面的代码，确保每个项目之间的间距为5px:

- (UIEdgeInsets)collectionView:(UICollectionView *) collectionView 
                        layout:(UICollectionViewLayout *) collectionViewLayout 
        insetForSectionAtIndex:(NSInteger) section {

    return UIEdgeInsetsMake(0, 0, 0, 5); // top, left, bottom, right
}

- (CGFloat)collectionView:(UICollectionView *) collectionView
                   layout:(UICollectionViewLayout *) collectionViewLayout
  minimumInteritemSpacingForSectionAtIndex:(NSInteger) section {    
    return 5.0;
}

使用水平流布局，我也得到了10点之间的单元格间距。为了移除间距，我需要将minimumlinespespaces和minimumInterItemSpacing设置为零。

UICollectionViewFlowLayout *flow = [[UICollectionViewFlowLayout alloc] init];
flow.itemSize = CGSizeMake(cellWidth, cellHeight);
flow.scrollDirection = UICollectionViewScrollDirectionHorizontal;
flow.minimumInteritemSpacing = 0;
flow.minimumLineSpacing = 0;

此外，如果所有单元格大小相同，直接在流布局上设置属性比使用委托方法更简单、更有效。

以前的版本并没有真正工作的部分> 1。所以我的解决方案在这里找到了https://codentrick.com/create-a-tag-flow-layout-with-uicollectionview/。对于懒惰的人:

override func layoutAttributesForElements(in rect: CGRect) -> [UICollectionViewLayoutAttributes]? {
    let attributesForElementsInRect = super.layoutAttributesForElements(in: rect)
    var newAttributesForElementsInRect = [UICollectionViewLayoutAttributes]()
    // use a value to keep track of left margin
    var leftMargin: CGFloat = 0.0;
    for attributes in attributesForElementsInRect! {
        let refAttributes = attributes 
        // assign value if next row
        if (refAttributes.frame.origin.x == self.sectionInset.left) {
            leftMargin = self.sectionInset.left
        } else {
            // set x position of attributes to current margin
            var newLeftAlignedFrame = refAttributes.frame
            newLeftAlignedFrame.origin.x = leftMargin
            refAttributes.frame = newLeftAlignedFrame
        }
        // calculate new value for current margin
        leftMargin += refAttributes.frame.size.width + 10
        newAttributesForElementsInRect.append(refAttributes)
    }

    return newAttributesForElementsInRect
}

在头文件中定义UICollectionViewDelegateFlowLayout协议。

实现UICollectionViewDelegateFlowLayout协议的如下方法:

- (UIEdgeInsets)collectionView:(UICollectionView *)collectionView layout:(UICollectionViewLayout*)collectionViewLayout insetForSectionAtIndex:(NSInteger)section
{
    return UIEdgeInsetsMake(5, 5, 5, 5);
}

点击这里查看苹果文档的UIEdgeInsetMake方法。

请注意属性名minimumInterItemSpacing。这将是项目之间的最小间距，而不是精确的间距。如果你设置minimumInterItemSpacing为某个值，你可以确保spacing不会小于该值。但有机会获得更高的价值。

实际上，项目之间的间距取决于几个因素itemSize和sectionInset。集合视图根据这些值动态放置内容。所以你不能保证精确的间距。你应该用sectionInset和minimumInterItemSpacing做一些试错。

Swift 3版本

简单地创建一个UICollectionViewFlowLayout子类并粘贴这个方法。

override func layoutAttributesForElements(in rect: CGRect) -> [UICollectionViewLayoutAttributes]? {
        guard let answer = super.layoutAttributesForElements(in: rect) else { return nil }

        for i in 1..<answer.count {
            let currentAttributes = answer[i]
            let previousAttributes = answer[i - 1]

            let maximumSpacing: CGFloat = 8
            let origin = previousAttributes.frame.maxX

            if (origin + maximumSpacing + currentAttributes.frame.size.width < self.collectionViewContentSize.width && currentAttributes.frame.origin.x > previousAttributes.frame.origin.x) {
                var frame = currentAttributes.frame
                frame.origin.x = origin + maximumSpacing
                currentAttributes.frame = frame
            }
        }

        return answer
}