请注意属性名minimumInterItemSpacing。这将是项目之间的最小间距，而不是精确的间距。如果你设置minimumInterItemSpacing为某个值，你可以确保spacing不会小于该值。但有机会获得更高的价值。

实际上，项目之间的间距取决于几个因素itemSize和sectionInset。集合视图根据这些值动态放置内容。所以你不能保证精确的间距。你应该用sectionInset和minimumInterItemSpacing做一些试错。

我偶然发现了与op类似的问题。不幸的是，接受的答案不适合我，因为collectionView的内容不会正确居中。因此，我提出了一个不同的解决方案，只需要在collectionView中的所有项目都具有相同的宽度，这似乎是问题中的情况:

#define cellSize 90

- (UIEdgeInsets)collectionView:(UICollectionView *)collectionView layout:(UICollectionViewLayout *)collectionViewLayout insetForSectionAtIndex:(NSInteger)section {
    float width = collectionView.frame.size.width;
    float spacing = [self collectionView:collectionView layout:collectionViewLayout minimumInteritemSpacingForSectionAtIndex:section];
    int numberOfCells = (width + spacing) / (cellSize + spacing);
    int inset = (width + spacing - numberOfCells * (cellSize + spacing) ) / 2;

    return UIEdgeInsetsMake(0, inset, 0, inset);
}

该代码将确保…minimumInteritemSpacing…将是每个collectionViewCell之间的精确间距，并进一步保证所有的单元格一起将在collectionView

试试下面的代码，确保每个项目之间的间距为5px:

- (UIEdgeInsets)collectionView:(UICollectionView *) collectionView 
                        layout:(UICollectionViewLayout *) collectionViewLayout 
        insetForSectionAtIndex:(NSInteger) section {

    return UIEdgeInsetsMake(0, 0, 0, 5); // top, left, bottom, right
}

- (CGFloat)collectionView:(UICollectionView *) collectionView
                   layout:(UICollectionViewLayout *) collectionViewLayout
  minimumInteritemSpacingForSectionAtIndex:(NSInteger) section {    
    return 5.0;
}

Swift 5 UIKit编程

 //Create UICollectionView
lazy var collectionView: UICollectionView = {
    
    let layout = UICollectionViewFlowLayout()
    layout.scrollDirection = .horizontal
    
    //CollectionCellView width autoSize
    layout.estimatedItemSize = UICollectionViewFlowLayout.automaticSize
    
    let collectionView = UICollectionView(frame: .zero, collectionViewLayout: layout)
    collectionView.translatesAutoresizingMaskIntoConstraints = false
    
    collectionView.register(CustomCollectionViewCell.self, forCellWithReuseIdentifier: cellId)
    collectionView.backgroundColor = .clear
    collectionView.delegate = self
    collectionView.dataSource = self
    collectionView.alwaysBounceHorizontal = true

//Add Spacing in each cell
    layout.minimumInteritemSpacing = 15
    layout.minimumLineSpacing = 15
    
    return collectionView
}()

投票的答案(以及快速版本)有一个小问题:右边会有一个很大的空格。

这是因为流布局是定制的，以使单元格间距精确，具有浮动左行为。

我的解决方案是操纵部分插入，使部分是对齐中心，但间距是完全指定的。

在下面的截图中，项目/行间距正好是8pt，而左右插入部分将大于8pt(使其居中对齐):

这样的Swift代码:

private let minItemSpacing: CGFloat = 8
private let itemWidth: CGFloat      = 100
private let headerHeight: CGFloat   = 32

override func viewDidLayoutSubviews() {
    super.viewDidLayoutSubviews()

    // Create our custom flow layout that evenly space out the items, and have them in the center
    let layout = UICollectionViewFlowLayout()
    layout.itemSize = CGSize(width: itemWidth, height: itemWidth)
    layout.minimumInteritemSpacing = minItemSpacing
    layout.minimumLineSpacing = minItemSpacing
    layout.headerReferenceSize = CGSize(width: 0, height: headerHeight)

    // Find n, where n is the number of item that can fit into the collection view
    var n: CGFloat = 1
    let containerWidth = collectionView.bounds.width
    while true {
        let nextN = n + 1
        let totalWidth = (nextN*itemWidth) + (nextN-1)*minItemSpacing
        if totalWidth > containerWidth {
            break
        } else {
            n = nextN
        }
    }

    // Calculate the section inset for left and right. 
    // Setting this section inset will manipulate the items such that they will all be aligned horizontally center.
    let inset = max(minItemSpacing, floor( (containerWidth - (n*itemWidth) - (n-1)*minItemSpacing) / 2 ) )
    layout.sectionInset = UIEdgeInsets(top: minItemSpacing, left: inset, bottom: minItemSpacing, right: inset)

    collectionView.collectionViewLayout = layout
}

我尝试了iago849的答案，它起作用了。

斯威夫特4

open override func layoutAttributesForElements(in rect: CGRect) -> [UICollectionViewLayoutAttributes]? {
    guard let answer = super.layoutAttributesForElements(in: rect) else {
        return nil
    }
    let count = answer.count
    for i in 1..<count {
        let currentLayoutAttributes = answer[i]
        let prevLayoutAttributes = answer[i-1]
        let origin = prevLayoutAttributes.frame.maxX
        if (origin + CGFloat(spacing) + currentLayoutAttributes.frame.size.width) < self.collectionViewContentSize.width && currentLayoutAttributes.frame.origin.x > prevLayoutAttributes.frame.origin.x {
            var frame = currentLayoutAttributes.frame
            frame.origin.x = origin + CGFloat(spacing)
            currentLayoutAttributes.frame = frame
        }
    }
    return answer
}

这是github项目的链接。 https://github.com/vishalwaka/MultiTags