如果您在IIS中使用Web发布特性，那么我发现的解决方案是编辑发布配置并从配置中删除Destination URL(让它为空)。

如果定义了这个，那么每次发布项目时，它都会打开Destination URL中指定的URL(这是一个重定向URL)。

参考:https://support.winhost.com/kb/a1604/visual-studio-publish-web-deploy.aspx

I looked over the answers and didn't see the solution I found mentioned. If it was, my apologies. In my case, currently using Visual Studio 2015. In the solution explorer, right click on the Project file and click properties. Go to the Debug tab and this should have info for how you're launching "IIS Express or Web(DNX)" for the first two drop downs, and then there should be a checkmark box for "Launch URL:". Uncheck this option and your browser won't be automatically launched everytime you go to debug your application. Hope this helps someone out.

打开启动项目的属性(project→{ProjectName} properties…从主菜单或在“解决方案资源管理器”中右键单击项目并选择“属性”)，然后导航到“Web”选项卡，在“开始操作”下选择“不打开页面”。等待来自外部应用程序的请求。

您仍然可以使用任何浏览器(或Fiddler，无论什么)来访问正在运行的应用程序，但它不会自动打开浏览器窗口，它只是在后台启动并等待任何请求。

当你第一次打开一个web/应用程序项目时，按Ctrl-F5，这是启动应用程序而不调试的快捷方式。然后，当您随后按下F5并启动调试器时，它将使用该IE实例。然后在Visual Studio中停止并启动调试，而不是关闭IE。

它在我的机器上工作。我正在使用内置的开发web服务器。不知道这有什么区别。

Firefox也将保持打开状态，因此您可以同时在其中一个或两个中进行调试。

There seems to be one case in which none of the above but the following helps. I'm developing a project for Windows Azure cloud platform and I have a web role. There is indeed a radio button Don't open page in Project -> {Project name} properties... as was pointed out by Pawel Krakowiak, but it has no effect in my case whatsoever. However, there is the main cloud project in solution explorer and there is the Roles folder under it. If I right click my web role in this folder and choose Properties, I get another set of settings and on the Configuration tab there is the Launch browser for flag, after unchecking it a new browser window is not opened on application start up.

.NET核心Web Api项目的更新答案…

右键单击项目，选择“属性”，转到“调试”，取消“启动浏览器”复选框(默认启用)。