对克雷格·塞莱斯特的答案进行了增强，任何人都可以使用它。out参数为IsAny:

public interface IService
{
    void DoSomething(out string a);
}

[TestMethod]
public void Test()
{
    var service = GetService();
    string actualValue;
    service.Object.DoSomething(out actualValue);
    Assert.AreEqual(expectedValue, actualValue);
}

private IService GetService()
{
    var service = new Mock<IService>();
    var anyString = It.IsAny<string>();
    service.Setup(s => s.DoSomething(out anyString))
        .Callback((out string providedString) => 
        {
            providedString = "SomeValue";
        });
    return service.Object;
}

如果你的方法也需要返回一些东西，你也可以使用Returns而不是Callback。

下面是一个正在工作的例子。

[Fact]
public void DeclineLowIncomeApplicationsOutDemo()
{
    var mockValidator = new Mock<IFrequentFlyerNumberValidator>();

    var isValid = true; // Whatever we set here, thats what we will get.

    mockValidator.Setup(x => x.IsValid(It.IsAny<string>(), out isValid));

    var sut = new CreditCardApplicationEvaluator(mockValidator.Object);

    var application = new CreditCardApplication
    {
        GrossAnnualIncome = 19_999,
        Age = 42
    };

    var decision = sut.EvaluateUsingOut(application);

    Assert.Equal(CreditCardApplicationDecision.AutoDeclined, decision);
}

public interface IFrequentFlyerNumberValidator
{
    bool IsValid(string frequentFlyerNumber);
    void IsValid(string frequentFlyerNumber, out bool isValid);
}

注意，在设置中没有return，因为没有return。

Moq版本4.8(或更高版本)对by-ref参数的支持有了很大的改进:

public interface IGobbler
{
    bool Gobble(ref int amount);
}

delegate void GobbleCallback(ref int amount);     // needed for Callback
delegate bool GobbleReturns(ref int amount);      // needed for Returns

var mock = new Mock<IGobbler>();
mock.Setup(m => m.Gobble(ref It.Ref<int>.IsAny))  // match any value passed by-ref
    .Callback(new GobbleCallback((ref int amount) =>
     {
         if (amount > 0)
         {
             Console.WriteLine("Gobbling...");
             amount -= 1;
         }
     }))
    .Returns(new GobbleReturns((ref int amount) => amount > 0));

int a = 5;
bool gobbleSomeMore = true;
while (gobbleSomeMore)
{
    gobbleSomeMore = mock.Object.Gobble(ref a);
}

同样的模式也适用于参数。

It.Ref < T >。IsAny也适用于c# 7的参数(因为它们也是by-ref)。

在Billy Jakes awnser的基础上，我用一个out参数做了一个完全动态的模拟方法。我把这个贴在这里给那些觉得有用的人。

// Define a delegate with the params of the method that returns void.
delegate void methodDelegate(int x, out string output);

// Define a variable to store the return value.
bool returnValue;

// Mock the method: 
// Do all logic in .Callback and store the return value.
// Then return the return value in the .Returns
mockHighlighter.Setup(h => h.SomeMethod(It.IsAny<int>(), out It.Ref<int>.IsAny))
  .Callback(new methodDelegate((int x, out int output) =>
  {
    // do some logic to set the output and return value.
    output = ...
    returnValue = ...
  }))
  .Returns(() => returnValue);

就像这样:

被嘲笑的方法是

public bool GenerateClient(out Client client);

那么模拟部分将是:

Client client = new Client();
clintMockBll
.Setup(x => x.GenerateClient(out client))
.Returns((Client client1) =>
{
   client = new Client(){Name="Something"};
   return true;
});

这是来自Moq网站的文档:

// out arguments
var outString = "ack";
// TryParse will return true, and the out argument will return "ack", lazy evaluated
mock.Setup(foo => foo.TryParse("ping", out outString)).Returns(true);


// ref arguments
var instance = new Bar();
// Only matches if the ref argument to the invocation is the same instance
mock.Setup(foo => foo.Submit(ref instance)).Returns(true);