该方法使用：

使用三引号字符串几乎没有内部标点符号使用检查模块去除局部压痕account_id和def_id变量使用Python 3.6格式的字符串插值（'f'）。

这种方式在我看来是最有蟒蛇风格的。

import inspect

query = inspect.cleandoc(f'''
    SELECT action.descr as "action",
    role.id as role_id,
    role.descr as role
    FROM
    public.role_action_def,
    public.role,
    public.record_def,
    public.action
    WHERE role.id = role_action_def.role_id AND
    record_def.id = role_action_def.def_id AND
    action.id = role_action_def.action_id AND
    role_action_def.account_id = {account_id} AND
    record_def.account_id={account_id} AND
    def_id={def_id}'''
)

我发现自己对这个很满意：

string = """This is a
very long string,
containing commas,
that I split up
for readability""".replace('\n',' ')

您还可以将SQL语句放置在单独的文件action.SQL中，并使用以下命令将其加载到.py文件中：

with open('action.sql') as f:
   query = f.read()

因此，SQL语句将与Python代码分离。如果SQL语句中有需要从Python填充的参数，则可以使用字符串格式（如%s或｛field｝）。

我通常用这样的词：

text = '''
    This string was typed to be a demo
    on how could we write a multi-line
    text in Python.
'''

如果要删除每行中烦人的空格，可以执行以下操作：

text = '\n'.join(line.lstrip() for line in text.splitlines())

其他人已经提到了圆括号方法，但我想补充一点，使用圆括号时，允许内联注释。

对每个片段的注释：

nursery_rhyme = (
    'Mary had a little lamb,'          # Comments are great!
    'its fleece was white as snow.'
    'And everywhere that Mary went,'
    'her sheep would surely go.'       # What a pesky sheep.
)

继续后不允许注释：

使用反斜杠行延续符（\）时，不允许使用注释。您将收到一个SyntaxError：一行接一行的连续字符错误。

nursery_rhyme = 'Mary had a little lamb,' \  # These comments
    'its fleece was white as snow.'       \  # are invalid!
    'And everywhere that Mary went,'      \
    'her sheep would surely go.'
# => SyntaxError: unexpected character after line continuation character

Regex字符串的更好注释：

基于以下示例https://docs.python.org/3/library/re.html#re.VERBOSE,

a = re.compile(
    r'\d+'  # the integral part
    r'\.'   # the decimal point
    r'\d*'  # some fractional digits
)

# Using VERBOSE flag, IDE usually can't syntax highight the string comment.
a = re.compile(r"""\d +  # the integral part
                   \.    # the decimal point
                   \d *  # some fractional digits""", re.X)

例如：

sql = ("select field1, field2, field3, field4 "
       "from table "
       "where condition1={} "
       "and condition2={}").format(1, 2)

Output: 'select field1, field2, field3, field4 from table
         where condition1=1 and condition2=2'

如果条件的值应该是字符串，可以这样做：

sql = ("select field1, field2, field3, field4 "
       "from table "
       "where condition1='{0}' "
       "and condition2='{1}'").format('2016-10-12', '2017-10-12')

Output: "select field1, field2, field3, field4 from table where
         condition1='2016-10-12' and condition2='2017-10-12'"