我会这样做:

# raw_input returns the empty string for "enter"
yes = {'yes','y', 'ye', ''}
no = {'no','n'}

choice = raw_input().lower()
if choice in yes:
   return True
elif choice in no:
   return False
else:
   sys.stdout.write("Please respond with 'yes' or 'no'")

Python x.x

res = True
while res:
    res = input("Please confirm with y/yes...").lower(); res = res not in {'y','yes','Y','YES',''}

正如Alexander Artemenko提到的，这里有一个使用strtobool()的简单解决方案。

from distutils.util import strtobool

def user_yes_no_query(question):
    sys.stdout.write('%s [y/n]\n' % question)
    while True:
        try:
            return strtobool(raw_input().lower())
        except ValueError:
            sys.stdout.write('Please respond with \'y\' or \'n\'.\n')

使用

>>> user_yes_no_query('Do you like cheese?')
Do you like cheese? [y/n]
Only on tuesdays
Please respond with 'y' or 'n'.
ok
Please respond with 'y' or 'n'.
y
>>> True

这是我对它的看法，我只是想中止如果用户没有确认的行动。

import distutils

if unsafe_case:
    print('Proceed with potentially unsafe thing? [y/n]')
    while True:
        try:
            verify = distutils.util.strtobool(raw_input())
            if not verify:
                raise SystemExit  # Abort on user reject
            break
        except ValueError as err:
            print('Please enter \'yes\' or \'no\'')
            # Try again
    print('Continuing ...')
do_unsafe_thing()

在2.7中，这是不是太非python化了?

if raw_input('your prompt').lower()[0]=='y':
   your code here
else:
   alternate code here

它至少能捕捉到“是”的任何变化。

我修改了fmark的答案，用python 2/3兼容更pythonic。

如果您对更多错误处理感兴趣，请参阅ipython的实用程序模块

# PY2/3 compatibility
from __future__ import print_function
# You could use the six package for this
try:
    input_ = raw_input
except NameError:
    input_ = input

def query_yes_no(question, default=True):
    """Ask a yes/no question via standard input and return the answer.

    If invalid input is given, the user will be asked until
    they acutally give valid input.

    Args:
        question(str):
            A question that is presented to the user.
        default(bool|None):
            The default value when enter is pressed with no value.
            When None, there is no default value and the query
            will loop.
    Returns:
        A bool indicating whether user has entered yes or no.

    Side Effects:
        Blocks program execution until valid input(y/n) is given.
    """
    yes_list = ["yes", "y"]
    no_list = ["no", "n"]

    default_dict = {  # default => prompt default string
        None: "[y/n]",
        True: "[Y/n]",
        False: "[y/N]",
    }

    default_str = default_dict[default]
    prompt_str = "%s %s " % (question, default_str)

    while True:
        choice = input_(prompt_str).lower()

        if not choice and default is not None:
            return default
        if choice in yes_list:
            return True
        if choice in no_list:
            return False

        notification_str = "Please respond with 'y' or 'n'"
        print(notification_str)