最简单的解决方案是在间隔之后获取同一个文件的两个实例并进行比较。你可以试试这样的东西

    while True:
        # Capturing the two instances models.py after certain interval of time
        print("Looking for changes in " + app_name.capitalize() + " models.py\nPress 'CTRL + C' to stop the program")
        with open(app_name.capitalize() + '/filename', 'r+') as app_models_file:
            filename_content = app_models_file.read()
        time.sleep(5)
        with open(app_name.capitalize() + '/filename', 'r+') as app_models_file_1:
            filename_content_1 = app_models_file_1.read()
        # Comparing models.py after certain interval of time
        if filename_content == filename_content_1:
            pass
        else:
            print("You made a change in " + app_name.capitalize() + " filename.\n")
            cmd = str(input("Do something with the file?(y/n):"))
            if cmd == 'y':
                # Do Something
            elif cmd == 'n':
                # pass or do something
            else:
                print("Invalid input")

正如您在Tim Golden的文章(由Horst Gutmann指出)中看到的，WIN32相对复杂，它监视目录，而不是单个文件。

我建议你研究一下IronPython，它是一个。net python实现。 在IronPython中，你可以使用所有的。net功能——包括

System.IO.FileSystemWatcher

它用一个简单的Event接口处理单个文件。

因为没有人提到它，所以我要把它放在那里:在标准库中有一个名为filecmp的Python模块，它有这个cmp()函数来比较两个文件。

只是要确保你没有使用from filecmp import cmp来掩盖Python 2.x中内置的cmp()函数。这在Python 3中是可以的。X，因为不再有这样的内置cmp()函数了。

不管怎样，它的用法是这样的:

import filecmp
filecmp.cmp(path_to_file_1, path_to_file_2, shallow=True)

参数shallow默认为True。如果参数的值为True，则只比较文件的元数据;但是，如果参数的值为False，则比较文件的内容。

也许这个信息对某人有用。

相关@4Oh4解决方案一个流畅的更改文件列表观看;

import os
import sys
import time

class Watcher(object):
    running = True
    refresh_delay_secs = 1

    # Constructor
    def __init__(self, watch_files, call_func_on_change=None, *args, **kwargs):
        self._cached_stamp = 0
        self._cached_stamp_files = {}
        self.filenames = watch_files
        self.call_func_on_change = call_func_on_change
        self.args = args
        self.kwargs = kwargs

    # Look for changes
    def look(self):
        for file in self.filenames:
            stamp = os.stat(file).st_mtime
            if not file in self._cached_stamp_files:
                self._cached_stamp_files[file] = 0
            if stamp != self._cached_stamp_files[file]:
                self._cached_stamp_files[file] = stamp
                # File has changed, so do something...
                file_to_read = open(file, 'r')
                value = file_to_read.read()
                print("value from file", value)
                file_to_read.seek(0)
                if self.call_func_on_change is not None:
                    self.call_func_on_change(*self.args, **self.kwargs)

    # Keep watching in a loop
    def watch(self):
        while self.running:
            try:
                # Look for changes
                time.sleep(self.refresh_delay_secs)
                self.look()
            except KeyboardInterrupt:
                print('\nDone')
                break
            except FileNotFoundError:
                # Action on file not found
                pass
            except Exception as e:
                print(e)
                print('Unhandled error: %s' % sys.exc_info()[0])

# Call this function each time a change happens
def custom_action(text):
    print(text)
    # pass

watch_files = ['/Users/mexekanez/my_file.txt', '/Users/mexekanez/my_file1.txt']

# watcher = Watcher(watch_file)  # simple



if __name__ == "__main__":
    watcher = Watcher(watch_files, custom_action, text='yes, changed')  # also call custom action function
    watcher.watch()  # start the watch going

看看pyinotify。

Inotify在新的linux中取代了dnotify(从以前的答案)，并允许文件级而不是目录级监控。

对我来说，最简单的解决方法就是使用看门狗的工具watchmedo

从https://pypi.python.org/pypi/watchdog我现在有一个进程，在一个目录中查找sql文件，并在必要时执行它们。

watchmedo shell-command \
--patterns="*.sql" \
--recursive \
--command='~/Desktop/load_files_into_mysql_database.sh' \
.