谢谢大家的帮助，这是我尝试的代码，这是为我工作

   UILabel *instructions = [[UILabel alloc]initWithFrame:CGRectMake(10, 225, 300, 180)];
   NSString *text = @"First take clear picture and then try to zoom in to fit the ";
   instructions.text = text;
   instructions.textAlignment = UITextAlignmentCenter;
   instructions.lineBreakMode = NSLineBreakByWordWrapping;
   [instructions setTextColor:[UIColor grayColor]];

   CGSize expectedLabelSize = [text sizeWithFont:instructions.font 
                                constrainedToSize:instructions.frame.size
                                    lineBreakMode:UILineBreakModeWordWrap];

    CGRect newFrame = instructions.frame;
    newFrame.size.height = expectedLabelSize.height;
    instructions.frame = newFrame;
    instructions.numberOfLines = 0;
    [instructions sizeToFit];
    [self addSubview:instructions];

我计算UILabel动态高度的方法。

    let width = ... //< width of this label 
    let text = ... //< display content

    label.numberOfLines = 0
    label.lineBreakMode = .byWordWrapping
    label.preferredMaxLayoutWidth = width

    // Font of this label.
    //label.font = UIFont.systemFont(ofSize: 17.0)
    // Compute intrinsicContentSize based on font, and preferredMaxLayoutWidth
    label.invalidateIntrinsicContentSize() 
    // Destination height
    let height = label.intrinsicContentSize.height

包装功能:

func computeHeight(text: String, width: CGFloat) -> CGFloat {
    // A dummy label in order to compute dynamic height.
    let label = UILabel()

    label.numberOfLines = 0
    label.lineBreakMode = .byWordWrapping
    label.font = UIFont.systemFont(ofSize: 17.0)

    label.preferredMaxLayoutWidth = width
    label.text = text
    label.invalidateIntrinsicContentSize()

    let height = label.intrinsicContentSize.height
    return height
}

对我来说，最简单和更好的方法是将高度约束应用于标签，并将优先级设置为低，即storyboard中的(250)。

所以你不需要担心通过编程计算高度和宽度，多亏了storyboard。

基于Swift 4及以上答案的UILabel扩展

extension UILabel {

    func retrieveTextHeight () -> CGFloat {
        let attributedText = NSAttributedString(string: self.text!, attributes: [NSFontAttributeName:self.font])

        let rect = attributedText.boundingRect(with: CGSize(width: self.frame.size.width, height: CGFloat.greatestFiniteMagnitude), options: .usesLineFragmentOrigin, context: nil)

        return ceil(rect.size.height)
    }

}

可以这样使用:

self.labelHeightConstraint.constant = self.label.retrieveTextHeight()

当自动布局被启用时，调整大小不工作:)

myLabel.text = "your very long text"
myLabel.numberOfLines = 0
myLabel.lineBreakMode = NSLineBreakMode.ByWordWrapping

请在故事板中为可用性设置约束，包括左上右下