你的方向是对的。你所需要做的就是:

myUILabel.numberOfLines = 0;
myUILabel.text = @"Enter large amount of text here";
[myUILabel sizeToFit];

对于那些迁移到iOS 8的人，这里有一个Swift的类扩展:

extension UILabel {

    func autoresize() {
        if let textNSString: NSString = self.text {
            let rect = textNSString.boundingRectWithSize(CGSizeMake(self.frame.size.width, CGFloat.max),
                options: NSStringDrawingOptions.UsesLineFragmentOrigin,
                attributes: [NSFontAttributeName: self.font],
                context: nil)
            self.frame = CGRectMake(self.frame.origin.x, self.frame.origin.y, self.frame.size.width, rect.height)
        }
    }

}

sizeWithFont constrainedToSize:lineBreakMode:是使用的方法。如何使用它的例子如下:

//Calculate the expected size based on the font and linebreak mode of your label
// FLT_MAX here simply means no constraint in height
CGSize maximumLabelSize = CGSizeMake(296, FLT_MAX);

CGSize expectedLabelSize = [yourString sizeWithFont:yourLabel.font constrainedToSize:maximumLabelSize lineBreakMode:yourLabel.lineBreakMode];   

//adjust the label the the new height.
CGRect newFrame = yourLabel.frame;
newFrame.size.height = expectedLabelSize.height;
yourLabel.frame = newFrame;

这种方法可以得到完美的高度

-(float) getHeightForText:(NSString*) text withFont:(UIFont*) font andWidth:(float) width{
CGSize constraint = CGSizeMake(width , 20000.0f);
CGSize title_size;
float totalHeight;


title_size = [text boundingRectWithSize:constraint
                                options:NSStringDrawingUsesLineFragmentOrigin
                             attributes:@{ NSFontAttributeName : font }
                                context:nil].size;

totalHeight = ceil(title_size.height);

CGFloat height = MAX(totalHeight, 40.0f);
return height;
}

对我来说，最简单和更好的方法是将高度约束应用于标签，并将优先级设置为低，即storyboard中的(250)。

所以你不需要担心通过编程计算高度和宽度，多亏了storyboard。

谢谢大家的帮助，这是我尝试的代码，这是为我工作

   UILabel *instructions = [[UILabel alloc]initWithFrame:CGRectMake(10, 225, 300, 180)];
   NSString *text = @"First take clear picture and then try to zoom in to fit the ";
   instructions.text = text;
   instructions.textAlignment = UITextAlignmentCenter;
   instructions.lineBreakMode = NSLineBreakByWordWrapping;
   [instructions setTextColor:[UIColor grayColor]];

   CGSize expectedLabelSize = [text sizeWithFont:instructions.font 
                                constrainedToSize:instructions.frame.size
                                    lineBreakMode:UILineBreakModeWordWrap];

    CGRect newFrame = instructions.frame;
    newFrame.size.height = expectedLabelSize.height;
    instructions.frame = newFrame;
    instructions.numberOfLines = 0;
    [instructions sizeToFit];
    [self addSubview:instructions];