以下是Vishwanath的解决方案，稍微写了一些注释:

function setStyle(cssRules, aSelector, aStyle){
    for(var i = 0; i < cssRules.length; i++) {
        if(cssRules[i].selectorText && cssRules[i].selectorText.toLowerCase() == aSelector.toLowerCase()) {
            cssRules[i].style.cssText = aStyle;
            return true;
        }
    }
    return false;
}

function createCSSSelector(selector, style) {
    var doc = document;
    var allSS = doc.styleSheets;
    if(!allSS) return;

    var headElts = doc.getElementsByTagName("head");
    if(!headElts.length) return;

    var styleSheet, media, iSS = allSS.length; // scope is global in a function
    /* 1. search for media == "screen" */
    while(iSS){ --iSS;
        if(allSS[iSS].disabled) continue; /* dont take into account the disabled stylesheets */
        media = allSS[iSS].media;
        if(typeof media == "object")
            media = media.mediaText;
        if(media == "" || media=='all' || media.indexOf("screen") != -1){
            styleSheet = allSS[iSS];
            iSS = -1;   // indication that media=="screen" was found (if not, then iSS==0)
            break;
        }
    }

    /* 2. if not found, create one */
    if(iSS != -1) {
        var styleSheetElement = doc.createElement("style");
        styleSheetElement.type = "text/css";
        headElts[0].appendChild(styleSheetElement);
        styleSheet = doc.styleSheets[allSS.length]; /* take the new stylesheet to add the selector and the style */
    }

    /* 3. add the selector and style */
    switch (typeof styleSheet.media) {
    case "string":
        if(!setStyle(styleSheet.rules, selector, style));
            styleSheet.addRule(selector, style);
        break;
    case "object":
        if(!setStyle(styleSheet.cssRules, selector, style));
            styleSheet.insertRule(selector + "{" + style + "}", styleSheet.cssRules.length);
        break;
    }

YUI拥有迄今为止我所见过的最好的样式表实用程序。我鼓励你去看看，但这里有一个味道:

// style element or locally sourced link element
var sheet = YAHOO.util.StyleSheet(YAHOO.util.Selector.query('style',null,true));

sheet = YAHOO.util.StyleSheet(YAHOO.util.Dom.get('local'));


// OR the id of a style element or locally sourced link element
sheet = YAHOO.util.StyleSheet('local');


// OR string of css text
var css = ".moduleX .alert { background: #fcc; font-weight: bold; } " +
          ".moduleX .warn  { background: #eec; } " +
          ".hide_messages .moduleX .alert, " +
          ".hide_messages .moduleX .warn { display: none; }";

sheet = new YAHOO.util.StyleSheet(css);

There are obviously other much simpler ways of changing styles on the fly such as those suggested here. If they make sense for your problem, they might be best, but there are definitely reasons why modifying CSS is a better solution. The most obvious case is when you need to modify a large number of elements. The other major case is if you need your style changes to involve the cascade. Using the DOM to modify an element will always have a higher priority. It's the sledgehammer approach and is equivalent to using the style attribute directly on the HTML element. That is not always the desired effect.

这里有一个选项:

var style = document.createElement（'style'）; style.type = 'text/css'; style.innerHTML = '.cssClass { color： #f00; }'; document.getElementsByTagName（'head'）[0].appendChild（style）; document.getElementById（'someElementId'）.className = 'cssClass'; <div id=“someElementId”>test text</div>

https://jsfiddle.net/xk6Ut/256/

在JavaScript中动态创建和更新CSS类的一个选项:

使用样式元素创建CSS节 使用样式元素的ID，以便我们可以更新CSS 类

…

function writeStyles(styleName, cssText) {
    var styleElement = document.getElementById(styleName);
    if (styleElement) 
             document.getElementsByTagName('head')[0].removeChild(
        styleElement);
    styleElement = document.createElement('style');
    styleElement.type = 'text/css';
    styleElement.id = styleName;
    styleElement.innerHTML = cssText;
    document.getElementsByTagName('head')[0].appendChild(styleElement);
}

...

    var cssText = '.testDIV{ height:' + height + 'px !important; }';
    writeStyles('styles_js', cssText)

有一个轻量级的jQuery插件可以生成CSS声明:jQuery- injectcss

事实上，它使用JSS (JSON描述的CSS)，但是为了生成动态CSS样式表，它很容易处理。

$.injectCSS({
    "#test": {
        height: 123
    }
});

这是我在Angular中行之有效的方法: 在HTML中，我有按钮与编程创建的CSS与特定的ID:

    <button [id]="'hoverbutton1'+item.key" [ngClass]="getHoverButtonClass()">
        <mat-icon class="icon">open_in_new</mat-icon>
    </button>

在typescript中，我创建了CSS，并将其分配给给定ID的特定元素:

addClasses(){
  var style1 = document.createElement('style');
  style1.innerHTML = '.hoverbutton'+this.item.key+' { display: none; }';
  document.getElementsByTagName('head')[0].appendChild(style1);
}

getHoverButtonClass() {
  return "hoverbutton"+this.item.key
}

通过这种方式，我可以创建尽可能多的CSS类，并将它们单独分配给元素。：）