下面是我的实现，它通过一些修复为我工作。它将密钥和秘密短语的对齐增强为32字节，IV为16字节:

import base64
import hashlib
from Crypto import Random
from Crypto.Cipher import AES

class AESCipher(object):

    def __init__(self, key):
        self.bs = AES.block_size
        self.key = hashlib.sha256(key.encode()).digest()

    def encrypt(self, raw):
        raw = self._pad(raw)
        iv = Random.new().read(AES.block_size)
        cipher = AES.new(self.key, AES.MODE_CBC, iv)
        return base64.b64encode(iv + cipher.encrypt(raw.encode()))

    def decrypt(self, enc):
        enc = base64.b64decode(enc)
        iv = enc[:AES.block_size]
        cipher = AES.new(self.key, AES.MODE_CBC, iv)
        return self._unpad(cipher.decrypt(enc[AES.block_size:])).decode('utf-8')

    def _pad(self, s):
        return s + (self.bs - len(s) % self.bs) * chr(self.bs - len(s) % self.bs)

    @staticmethod
    def _unpad(s):
        return s[:-ord(s[len(s)-1:])]

请看mnothic的回答。

兼容UTF-8编码:

def _pad(self, s):
    s = s.encode()
    res = s + (self.bs - len(s) % self.bs) * chr(self.bs - len(s) % self.bs).encode()
    return res

对于想要使用urlsafe_b64encode和urlsafe_b64decode的人，这里是为我工作的版本(在花了一些时间与unicode问题之后)

BS = 16
key = hashlib.md5(settings.SECRET_KEY).hexdigest()[:BS]
pad = lambda s: s + (BS - len(s) % BS) * chr(BS - len(s) % BS)
unpad = lambda s : s[:-ord(s[len(s)-1:])]

class AESCipher:
    def __init__(self, key):
        self.key = key

    def encrypt(self, raw):
        raw = pad(raw)
        iv = Random.new().read(AES.block_size)
        cipher = AES.new(self.key, AES.MODE_CBC, iv)
        return base64.urlsafe_b64encode(iv + cipher.encrypt(raw)) 

    def decrypt(self, enc):
        enc = base64.urlsafe_b64decode(enc.encode('utf-8'))
        iv = enc[:BS]
        cipher = AES.new(self.key, AES.MODE_CBC, iv)
        return unpad(cipher.decrypt(enc[BS:]))

下面是我的实现，它通过一些修复为我工作。它将密钥和秘密短语的对齐增强为32字节，IV为16字节:

import base64
import hashlib
from Crypto import Random
from Crypto.Cipher import AES

class AESCipher(object):

    def __init__(self, key):
        self.bs = AES.block_size
        self.key = hashlib.sha256(key.encode()).digest()

    def encrypt(self, raw):
        raw = self._pad(raw)
        iv = Random.new().read(AES.block_size)
        cipher = AES.new(self.key, AES.MODE_CBC, iv)
        return base64.b64encode(iv + cipher.encrypt(raw.encode()))

    def decrypt(self, enc):
        enc = base64.b64decode(enc)
        iv = enc[:AES.block_size]
        cipher = AES.new(self.key, AES.MODE_CBC, iv)
        return self._unpad(cipher.decrypt(enc[AES.block_size:])).decode('utf-8')

    def _pad(self, s):
        return s + (self.bs - len(s) % self.bs) * chr(self.bs - len(s) % self.bs)

    @staticmethod
    def _unpad(s):
        return s[:-ord(s[len(s)-1:])]

from Crypto import Random
from Crypto.Cipher import AES
import base64

BLOCK_SIZE=16
def trans(key):
     return md5.new(key).digest()

def encrypt(message, passphrase):
    passphrase = trans(passphrase)
    IV = Random.new().read(BLOCK_SIZE)
    aes = AES.new(passphrase, AES.MODE_CFB, IV)
    return base64.b64encode(IV + aes.encrypt(message))

def decrypt(encrypted, passphrase):
    passphrase = trans(passphrase)
    encrypted = base64.b64decode(encrypted)
    IV = encrypted[:BLOCK_SIZE]
    aes = AES.new(passphrase, AES.MODE_CFB, IV)
    return aes.decrypt(encrypted[BLOCK_SIZE:])

我很感激其他启发我的答案，但它们对我不起作用。

在花了几个小时试图弄清楚它是如何工作的之后，我用最新的PyCryptodomex库提出了下面的实现(这是另一个故事，我如何设法在代理后面设置它，在Windows上，在virtualenv中…唷)

它正在处理您的实现。记得写下填充、编码和加密步骤(反之亦然)。你必须打包和拆包，记住顺序。

import base64
import hashlib
from Cryptodome.Cipher import AES
from Cryptodome.Random import get_random_bytes

__key__ = hashlib.sha256(b'16-character key').digest()

def encrypt(raw):
    BS = AES.block_size
    pad = lambda s: s + (BS - len(s) % BS) * chr(BS - len(s) % BS)

    raw = base64.b64encode(pad(raw).encode('utf8'))
    iv = get_random_bytes(AES.block_size)
    cipher = AES.new(key= __key__, mode= AES.MODE_CFB,iv= iv)
    return base64.b64encode(iv + cipher.encrypt(raw))

def decrypt(enc):
    unpad = lambda s: s[:-ord(s[-1:])]

    enc = base64.b64decode(enc)
    iv = enc[:AES.block_size]
    cipher = AES.new(__key__, AES.MODE_CFB, iv)
    return unpad(base64.b64decode(cipher.decrypt(enc[AES.block_size:])).decode('utf8'))