由于目前的解决方案都不产生一个元组，我将抛出:

temp3 = tuple(set(temp1) - set(temp2))

另外:

#edited using @Mark Byers idea. If you accept this one as answer, just accept his instead.
temp3 = tuple(x for x in temp1 if x not in set(temp2))

像其他在这个方向上得到答案的非元组一样，它保持了顺序

获取在temp1中而不在temp2中的元素 (假设每个列表中的元素是唯一的):

In [5]: list(set(temp1) - set(temp2))
Out[5]: ['Four', 'Three']

注意它是不对称的 :

In [5]: set([1, 2]) - set([2, 3])
Out[5]: set([1]) 

这里您可能期望/希望它等于set([1,3])。如果你想要set([1,3])作为你的答案，你可以使用set([1,2])。symmetric_difference(设置([2、3]))。

两个列表(例如list1和list2)之间的差异可以使用下面的简单函数找到。

def diff(list1, list2):
    c = set(list1).union(set(list2))  # or c = set(list1) | set(list2)
    d = set(list1).intersection(set(list2))  # or d = set(list1) & set(list2)
    return list(c - d)

or

def diff(list1, list2):
    return list(set(list1).symmetric_difference(set(list2)))  # or return list(set(list1) ^ set(list2))

通过使用上述函数，可以使用diff(temp2, temp1)或diff(temp1, temp2)找到差异。两者都会给出结果['Four'， 'Three']。你不需要担心列表的顺序或者先给出哪个列表。

Python文档参考

试试这个:

temp3 = set(temp1) - set(temp2)

def diffList(list1, list2):     # returns the difference between two lists.
    if len(list1) > len(list2):
        return (list(set(list1) - set(list2)))
    else:
        return (list(set(list2) - set(list1)))

例如，如果list1 =[10, 15, 20, 25, 30, 35, 40]和list2 =[25, 40, 35]，那么返回的列表将输出= [10,20,30,15]

如果您想要更类似于变更集的东西……可以使用Counter

from collections import Counter

def diff(a, b):
  """ more verbose than needs to be, for clarity """
  ca, cb = Counter(a), Counter(b)
  to_add = cb - ca
  to_remove = ca - cb
  changes = Counter(to_add)
  changes.subtract(to_remove)
  return changes

lista = ['one', 'three', 'four', 'four', 'one']
listb = ['one', 'two', 'three']

In [127]: diff(lista, listb)
Out[127]: Counter({'two': 1, 'one': -1, 'four': -2})
# in order to go from lista to list b, you need to add a "two", remove a "one", and remove two "four"s

In [128]: diff(listb, lista)
Out[128]: Counter({'four': 2, 'one': 1, 'two': -1})
# in order to go from listb to lista, you must add two "four"s, add a "one", and remove a "two"