import re
s = "string. With. Punctuation?" # Sample string 
out = re.sub(r'[^a-zA-Z0-9\s]', '', s)

这可能不是最好的解决方案，但我就是这样做的。

import string
f = lambda x: ''.join([i for i in x if i not in string.punctuation])

我通常用这样的词：

>>> s = "string. With. Punctuation?" # Sample string
>>> import string
>>> for c in string.punctuation:
...     s= s.replace(c,"")
...
>>> s
'string With Punctuation'

在不太严格的情况下，单行线可能会有所帮助：

''.join([c for c in s if c.isalnum() or c.isspace()])

>>> s = "string. With. Punctuation?"
>>> s = re.sub(r'[^\w\s]','',s)
>>> re.split(r'\s*', s)


['string', 'With', 'Punctuation']

with open('one.txt','r')as myFile:

    str1=myFile.read()

    print(str1)


    punctuation = ['(', ')', '?', ':', ';', ',', '.', '!', '/', '"', "'"] 

for i in punctuation:

        str1 = str1.replace(i," ") 
        myList=[]
        myList.extend(str1.split(" "))
print (str1) 
for i in myList:

    print(i,end='\n')
    print ("____________")