我也在寻找最好的方法来检查文本框中只有数字和键盘的问题是，它不支持通过右键单击或剪贴板复制粘贴，所以提出了这个代码，验证光标离开文本字段时，它也检查空字段。(newguy改编版)

private void txtFirstValue_MouseLeave(object sender, EventArgs e)
{
    int num;
    bool isNum = int.TryParse(txtFirstValue.Text.Trim(), out num);

    if (!isNum && txtFirstValue.Text != String.Empty)
    {
        MessageBox.Show("The First Value You Entered Is Not a Number, Please Try Again", "Invalid Value Detected", MessageBoxButtons.OK, MessageBoxIcon.Error);
        txtFirstValue.Clear();
    }
}

int Number;
bool isNumber;
isNumber = int32.TryPase(textbox1.text, out Number);

if (!isNumber)
{ 
    (code if not an integer);
}
else
{
    (code if an integer);
}

简单的回答是:

_textBox.TextChanged += delegate(System.Object o, System.EventArgs e)
{
    TextBox _tbox = o as TextBox;
    _tbox.Text = new string(_tbox.Text.Where(c => (char.IsDigit(c)) || (c == '.')).ToArray());
};

我一直致力于一个组件的集合来完成WinForms中缺失的东西，这里是:高级表单

特别地，这是一个正则文本框类

/// <summary>Represents a Windows text box control that only allows input that matches a regular expression.</summary>
public class RegexTextBox : TextBox
{
    [NonSerialized]
    string lastText;

    /// <summary>A regular expression governing the input allowed in this text field.</summary>
    [Browsable(false), EditorBrowsable(EditorBrowsableState.Never)]
    [DesignerSerializationVisibility(DesignerSerializationVisibility.Hidden)]
    public virtual Regex Regex { get; set; }

    /// <summary>A regular expression governing the input allowed in this text field.</summary>
    [DefaultValue(null)]
    [Category("Behavior")]
    [Description("Sets the regular expression governing the input allowed for this control.")]
    public virtual string RegexString {
        get {
            return Regex == null ? string.Empty : Regex.ToString();
        }
        set {
            if (string.IsNullOrEmpty(value))
                Regex = null;
            else
                Regex = new Regex(value);
        }
    }

    protected override void OnTextChanged(EventArgs e) {
        if (Regex != null && !Regex.IsMatch(Text)) {
            int pos = SelectionStart - Text.Length + (lastText ?? string.Empty).Length;
            Text = lastText;
            SelectionStart = Math.Max(0, pos);
        }

        lastText = Text;

        base.OnTextChanged(e);
    }
}

简单地添加像myNumbericTextBox这样的东西。RegexString = "^(\\d+|)$";应该足够了。

尝试一个MaskedTextBox。它采用一种简单的掩码格式，这样你就可以将输入限制为数字或日期之类的。

只是因为在一条线上做事情总是更有趣……

 private void textBox1_KeyPress(object sender, KeyPressEventArgs e)
    {
        e.Handled = !char.IsDigit(e.KeyChar) && !char.IsControl(e.KeyChar);
    }

注意:这并不阻止用户复制/粘贴到此文本框。这并不是清除数据的安全方法。