假设您有列为A、B、C的df。

最简单的方法是：

df = df.reindex(['B','C','A'], axis=1)

您可以使用可用于两个轴的重新索引：

df
#           0         1         2         3         4      mean
# 0  0.943825  0.202490  0.071908  0.452985  0.678397  0.469921
# 1  0.745569  0.103029  0.268984  0.663710  0.037813  0.363821
# 2  0.693016  0.621525  0.031589  0.956703  0.118434  0.484254
# 3  0.284922  0.527293  0.791596  0.243768  0.629102  0.495336
# 4  0.354870  0.113014  0.326395  0.656415  0.172445  0.324628
# 5  0.815584  0.532382  0.195437  0.829670  0.019001  0.478415
# 6  0.944587  0.068690  0.811771  0.006846  0.698785  0.506136
# 7  0.595077  0.437571  0.023520  0.772187  0.862554  0.538182
# 8  0.700771  0.413958  0.097996  0.355228  0.656919  0.444974
# 9  0.263138  0.906283  0.121386  0.624336  0.859904  0.555009

df.reindex(['mean', *range(5)], axis=1)

#        mean         0         1         2         3         4
# 0  0.469921  0.943825  0.202490  0.071908  0.452985  0.678397
# 1  0.363821  0.745569  0.103029  0.268984  0.663710  0.037813
# 2  0.484254  0.693016  0.621525  0.031589  0.956703  0.118434
# 3  0.495336  0.284922  0.527293  0.791596  0.243768  0.629102
# 4  0.324628  0.354870  0.113014  0.326395  0.656415  0.172445
# 5  0.478415  0.815584  0.532382  0.195437  0.829670  0.019001
# 6  0.506136  0.944587  0.068690  0.811771  0.006846  0.698785
# 7  0.538182  0.595077  0.437571  0.023520  0.772187  0.862554
# 8  0.444974  0.700771  0.413958  0.097996  0.355228  0.656919
# 9  0.555009  0.263138  0.906283  0.121386  0.624336  0.859904

我认为这是一个略为简洁的解决方案：

df.insert(0, 'mean', df.pop("mean"))

这个解决方案有点类似于@JoeHeffer的解决方案，但这是一条直线。

这里，我们从数据帧中删除列“mean”，并将其附加到具有相同列名的索引0。

我相信，如果你知道另一列的位置，@Aman的答案是最好的。

如果您不知道mean的位置，但只有它的名称，则不能直接使用cols=cols[-1:]+cols[：-1]。以下是我接下来能想到的最好的东西：

meanDf = pd.DataFrame(df.pop('mean'))
# now df doesn't contain "mean" anymore. Order of join will move it to left or right:
meanDf.join(df) # has mean as first column
df.join(meanDf) # has mean as last column

我想到了和Dmitriy Work一样的答案，显然是最简单的：

df["mean"] = df.mean(1)
l =  list(np.arange(0,len(df.columns) -1 ))
l.insert(0,-1)
df.iloc[:,l]

我有一个在panda中重新排序列名的非常具体的用例。有时我在基于现有列的数据帧中创建一个新列。默认情况下，panda将在末尾插入我的新列，但我希望新列插入到它派生的现有列旁边。

def rearrange_list(input_list, input_item_to_move, input_item_insert_here):
    '''
    Helper function to re-arrange the order of items in a list.
    Useful for moving column in pandas dataframe.

    Inputs:
        input_list - list
        input_item_to_move - item in list to move
        input_item_insert_here - item in list, insert before 

    returns:
        output_list
    '''
    # make copy for output, make sure it's a list
    output_list = list(input_list)

    # index of item to move
    idx_move = output_list.index(input_item_to_move)

    # pop off the item to move
    itm_move = output_list.pop(idx_move)

    # index of item to insert here
    idx_insert = output_list.index(input_item_insert_here)

    # insert item to move into here
    output_list.insert(idx_insert, itm_move)

    return output_list


import pandas as pd

# step 1: create sample dataframe
df = pd.DataFrame({
    'motorcycle': ['motorcycle1', 'motorcycle2', 'motorcycle3'],
    'initial_odometer': [101, 500, 322],
    'final_odometer': [201, 515, 463],
    'other_col_1': ['blah', 'blah', 'blah'],
    'other_col_2': ['blah', 'blah', 'blah']
})
print('Step 1: create sample dataframe')
display(df)
print()

# step 2: add new column that is difference between final and initial
df['change_odometer'] = df['final_odometer']-df['initial_odometer']
print('Step 2: add new column')
display(df)
print()

# step 3: rearrange columns
ls_cols = df.columns
ls_cols = rearrange_list(ls_cols, 'change_odometer', 'final_odometer')
df=df[ls_cols]
print('Step 3: rearrange columns')
display(df)