iis7或以上

使用此代码，但您需要是服务器上的管理员

public bool CheckMimeMapExtension(string fileExtension)
        {
            try
            {

                using (
                ServerManager serverManager = new ServerManager())
                {   
                    // connects to default app.config
                    var config = serverManager.GetApplicationHostConfiguration();
                    var staticContent = config.GetSection("system.webServer/staticContent");
                    var mimeMap = staticContent.GetCollection();

                    foreach (var mimeType in mimeMap)
                    {

                        if (((String)mimeType["fileExtension"]).Equals(fileExtension, StringComparison.OrdinalIgnoreCase))
                            return true;

                    }

                }
                return false;
            }
            catch (Exception ex)
            { 
                Console.WriteLine("An exception has occurred: \n{0}", ex.Message);
                Console.Read();
            }

            return false;

        }

I think the right answer is a combination of Steve Morgan's and Serguei's answers. That's how Internet Explorer does it. The pinvoke call to FindMimeFromData works for only 26 hard-coded mime types. Also, it will give ambigous mime types (such as text/plain or application/octet-stream) even though there may exist a more specific, more appropriate mime type. If it fails to give a good mime type, you can go to the registry for a more specific mime type. The server registry could have more up-to-date mime types.

参考网址:http://msdn.microsoft.com/en-us/library/ms775147(VS.85).aspx

@Steve Morgan和@Richard Gourlay，这是一个很好的解决方案，谢谢你们。一个小缺点是，当文件中的字节数为255或以下时，mime类型有时会产生“application/octet-stream”，这对于期望产生“text/plain”的文件来说有点不准确。对于这种情况，我更新了你原来的方法如下:

如果文件中的字节数小于或等于255，并且推导出的mime类型是"application/octet-stream"，那么创建一个新的字节数组，该数组由重复n次的原始文件字节组成，直到字节总数为>= 256。然后重新检查新字节数组上的mime-type。

修改方法:

Imports System.Runtime.InteropServices

<DllImport("urlmon.dll", CharSet:=CharSet.Auto)> _
Private Shared Function FindMimeFromData(pBC As System.UInt32, <MarshalAs(UnmanagedType.LPStr)> pwzUrl As System.String, <MarshalAs(UnmanagedType.LPArray)> pBuffer As Byte(), cbSize As System.UInt32, <MarshalAs(UnmanagedType.LPStr)> pwzMimeProposed As System.String, dwMimeFlags As System.UInt32, _
ByRef ppwzMimeOut As System.UInt32, dwReserverd As System.UInt32) As System.UInt32
End Function
Private Function GetMimeType(ByVal f As FileInfo) As String
    'See http://stackoverflow.com/questions/58510/using-net-how-can-you-find-the-mime-type-of-a-file-based-on-the-file-signature
    Dim returnValue As String = ""
    Dim fileStream As FileStream = Nothing
    Dim fileStreamLength As Long = 0
    Dim fileStreamIsLessThanBByteSize As Boolean = False

    Const byteSize As Integer = 255
    Const bbyteSize As Integer = byteSize + 1

    Const ambiguousMimeType As String = "application/octet-stream"
    Const unknownMimeType As String = "unknown/unknown"

    Dim buffer As Byte() = New Byte(byteSize) {}
    Dim fnGetMimeTypeValue As New Func(Of Byte(), Integer, String)(
        Function(_buffer As Byte(), _bbyteSize As Integer) As String
            Dim _returnValue As String = ""
            Dim mimeType As UInt32 = 0
            FindMimeFromData(0, Nothing, _buffer, _bbyteSize, Nothing, 0, mimeType, 0)
            Dim mimeTypePtr As IntPtr = New IntPtr(mimeType)
            _returnValue = Marshal.PtrToStringUni(mimeTypePtr)
            Marshal.FreeCoTaskMem(mimeTypePtr)
            Return _returnValue
        End Function)

    If (f.Exists()) Then
        Try
            fileStream = New FileStream(f.FullName(), FileMode.Open, FileAccess.Read, FileShare.ReadWrite)
            fileStreamLength = fileStream.Length()

            If (fileStreamLength >= bbyteSize) Then
                fileStream.Read(buffer, 0, bbyteSize)
            Else
                fileStreamIsLessThanBByteSize = True
                fileStream.Read(buffer, 0, CInt(fileStreamLength))
            End If

            returnValue = fnGetMimeTypeValue(buffer, bbyteSize)

            If (returnValue.Equals(ambiguousMimeType, StringComparison.OrdinalIgnoreCase) AndAlso fileStreamIsLessThanBByteSize AndAlso fileStreamLength > 0) Then
                'Duplicate the stream content until the stream length is >= bbyteSize to get a more deterministic mime type analysis.
                Dim currentBuffer As Byte() = buffer.Take(fileStreamLength).ToArray()
                Dim repeatCount As Integer = Math.Floor((bbyteSize / fileStreamLength) + 1)
                Dim bBufferList As List(Of Byte) = New List(Of Byte)
                While (repeatCount > 0)
                    bBufferList.AddRange(currentBuffer)
                    repeatCount -= 1
                End While
                Dim bbuffer As Byte() = bBufferList.Take(bbyteSize).ToArray()
                returnValue = fnGetMimeTypeValue(bbuffer, bbyteSize)
            End If
        Catch ex As Exception
            returnValue = unknownMimeType
        Finally
            If (fileStream IsNot Nothing) Then fileStream.Close()
        End Try
    End If
    Return returnValue
End Function

如果你想要托管你的ASP. mimetype，来自Nuget的guessmimetype将是最终的解决方案。NET解决方案在非windows环境。

文件扩展名映射非常不安全。如果攻击者上传无效的扩展名，映射字典将允许可执行文件在.jpg文件中分发。 因此，始终使用内容嗅探库来了解真正的内容类型。

 public  static string MimeTypeFrom(byte[] dataBytes, string fileName)
 {
        var contentType = HeyRed.Mime.MimeGuesser.GuessMimeType(dataBytes);
        if (string.IsNullOrEmpty(contentType))
        {
            return HeyRed.Mime.MimeTypesMap.GetMimeType(fileName);
        }
  return contentType;

如果你正在使用。net Framework 4.5或更高版本，现在有一个MimeMapping.GetMimeMapping(filename)方法，它将返回一个字符串，其中包含传递文件名的正确Mime映射。注意，这里使用的是文件扩展名，而不是文件本身中的数据。

文档请见http://msdn.microsoft.com/en-us/library/system.web.mimemapping.getmimemapping

iis7或以上

使用此代码，但您需要是服务器上的管理员

public bool CheckMimeMapExtension(string fileExtension)
        {
            try
            {

                using (
                ServerManager serverManager = new ServerManager())
                {   
                    // connects to default app.config
                    var config = serverManager.GetApplicationHostConfiguration();
                    var staticContent = config.GetSection("system.webServer/staticContent");
                    var mimeMap = staticContent.GetCollection();

                    foreach (var mimeType in mimeMap)
                    {

                        if (((String)mimeType["fileExtension"]).Equals(fileExtension, StringComparison.OrdinalIgnoreCase))
                            return true;

                    }

                }
                return false;
            }
            catch (Exception ex)
            { 
                Console.WriteLine("An exception has occurred: \n{0}", ex.Message);
                Console.Read();
            }

            return false;

        }