Mine didn't work for unit tests either, and for some reason Michael Bromley's answer involving DeploymentItem attribute didn't work. However, I got it working using test settings. In VS2013, add a new item to your solution and search for "settings" and select the "Test Settings" template file. Name it "SqliteUnitTests" or something and open it. Select "Deployment" off to the right, and add Directory/File. Add paths/directories to your SQLite.Interop.dll file. For me, I added two paths, one each for Project\bin\Debug\x64 and Console\bin\Debug\x86. You may also want to add your Sqlite file, depending on how you expect your unit test/solution to access the file.

在构建之前，尝试将平台目标设置为x86或x64(而不是任何CPU): 项目->属性->在Visual Studio中构建->平台目标。

当您处于这种状态时，尝试执行Rebuild-All。如果这解决了问题，您可能会遇到与我相同的问题。

一些背景(我的理解):

SQLite has 1 managed assembly (System.Data.SQLite.dll) and several platform specific assemblies (SQLite.Interop.dll). When installing SQLite with Nuget, Nuget will add the platform specific assemblies to your project (within several folders: \x86, \x64), and configures these dlls to "Copy Always". Upon load, the managed assembly will search for platform specific assemblies inside the \x86 and \x64 folders. You can see more on that here. The exception is this managed assembly attempting to find the relevant (SQLite.Interop.dll) inside these folders (and failing).

我的情况:

我的解决方案中有两个项目;一个WPF应用程序和一个类库。WPF应用程序引用类库，类库引用SQLite(通过Nuget安装)。

对我来说，问题是当我只修改WPF应用程序时，VS试图进行部分重建(意识到依赖的dll没有改变)。在这个过程的某个地方，VS清理了\x86和\x64文件夹的内容(清除了SQLite.Interop.dll)。当我做一个完整的Rebuild-All时，VS正确地复制文件夹及其内容。

我的解决方案:

为了解决这个问题，我添加了一个Post-Build进程，使用xcopy强制将\x86和\x64文件夹从类库复制到我的WPF项目\bin目录。

或者，您可以使用构建配置/输出目录做一些更花哨的事情。

这对我来说很管用。

With Visual Studio open, search and install SQLite.Core via the NUGET Package manager. Go to Solution Explorer in VS, Right click your PROJECT NAME-->ADD-->NEW FOLDER Name the folder x64 Repeat the process and add folder and name it x86 Right click the x64 folder-->ADD-->EXISTING ITEM Then browse to the DEBUG FOLDER. You will find the x64 folder. Open it and select the "SQLite.Interop.dll" file then hit OK. Repeat step 5 for the x86 folder. Right click the DLL that you just added and select PROPERTIES. In the option Copy to Output Directory, choose Copy always. Repeat step 7 for both DLLs in x64 and x86 folder.

下次构建该项目并使用另一台计算机时，它应该可以正常工作。

将x86和x64的“SQLite.Interop.dll”文件复制到调试文件夹中。这些文件应该复制到调试文件夹中的“x86”和“x64”文件夹中。

我不知道这是否是一个好的答案，但我能够通过在AppDomain下以“本地系统”的身份运行我的应用程序来解决这个问题。