你可以使用Linq的Aggregate函数:

string s = "the\nquick\tbrown\rdog,jumped;over the lazy fox.";
char[] chars = new char[] { ' ', ';', ',', '\r', '\t', '\n' };
string snew = chars.Aggregate(s, (c1, c2) => c1.Replace(c2, '\n'));

下面是扩展方法:

public static string ReplaceAll(this string seed, char[] chars, char replacementCharacter)
{
    return chars.Aggregate(seed, (str, cItem) => str.Replace(cItem, replacementCharacter));
}

扩展方法使用示例:

string snew = s.ReplaceAll(chars, '\n');

没有“替换”(仅限Linq):

    string myString = ";,\r\t \n\n=1;;2,,3\r\r4\t\t5  6\n\n\n\n7=";
    char NoRepeat = '\n';
    string ByeBye = ";,\r\t ";
    string myResult = myString.ToCharArray().Where(t => !"STOP-OUTSIDER".Contains(t))
                 .Select(t => "" + ( ByeBye.Contains(t) ? '\n' : t))
                  .Aggregate((all, next) => (
                      next == "" + NoRepeat && all.Substring(all.Length - 1) == "" + NoRepeat
                      ? all : all  + next ) );

使用正则表达式。替换，像这样:

  string input = "This is   text with   far  too   much   " + 
                 "whitespace.";
  string pattern = "[;,]";
  string replacement = "\n";
  Regex rgx = new Regex(pattern);
  string result = rgx.Replace(input, replacement);

这里是关于RegEx的MSDN文档的更多信息。取代

你可以使用Linq的Aggregate函数:

string s = "the\nquick\tbrown\rdog,jumped;over the lazy fox.";
char[] chars = new char[] { ' ', ';', ',', '\r', '\t', '\n' };
string snew = chars.Aggregate(s, (c1, c2) => c1.Replace(c2, '\n'));

下面是扩展方法:

public static string ReplaceAll(this string seed, char[] chars, char replacementCharacter)
{
    return chars.Aggregate(seed, (str, cItem) => str.Replace(cItem, replacementCharacter));
}

扩展方法使用示例:

string snew = s.ReplaceAll(chars, '\n');

就性能而言，这可能不是最好的解决方案，但它确实有效。

var str = "filename:with&bad$separators.txt";
char[] charArray = new char[] { '#', '%', '&', '{', '}', '\\', '<', '>', '*', '?', '/', ' ', '$', '!', '\'', '"', ':', '@' };
foreach (var singleChar in charArray)
{
   str = str.Replace(singleChar, '_');
}

字符串只是不可变的字符数组

你只需要让它可变:

或者使用StringBuilder 去不安全的世界玩指针(虽然很危险)

并尝试在字符数组中迭代最少的次数。注意这里的HashSet，因为它避免遍历循环中的字符序列。如果你需要更快的查找，你可以用优化的char查找(基于数组[256])替换HashSet。

StringBuilder示例

public static void MultiReplace(this StringBuilder builder, 
    char[] toReplace, 
    char replacement)
{
    HashSet<char> set = new HashSet<char>(toReplace);
    for (int i = 0; i < builder.Length; ++i)
    {
        var currentCharacter = builder[i];
        if (set.Contains(currentCharacter))
        {
            builder[i] = replacement;
        }
    }
}

编辑-优化版本(仅对ASCII有效)

public static void MultiReplace(this StringBuilder builder, 
    char[] toReplace,
    char replacement)
{
    var set = new bool[256];
    foreach (var charToReplace in toReplace)
    {
        set[charToReplace] = true;
    }
    for (int i = 0; i < builder.Length; ++i)
    {
        var currentCharacter = builder[i];
        if (set[currentCharacter])
        {
            builder[i] = replacement;
        }
    }
}

然后你就像这样使用它:

var builder = new StringBuilder("my bad,url&slugs");
builder.MultiReplace(new []{' ', '&', ','}, '-');
var result = builder.ToString();