以下是Swift版本的公认答案:

斯威夫特3:

let font = UIFont.systemFont(ofSize: 16)
segmentedControl.setTitleTextAttributes([NSFontAttributeName: font],
                                        for: .normal)

斯威夫特2.2:

let font = UIFont.systemFontOfSize(16)
segmentedControl.setTitleTextAttributes([NSFontAttributeName: font], 
    forState: UIControlState.Normal)

另一种选择是对控件应用转换。然而，它将缩小一切，包括控制边界。

segmentedControl.transform = CGAffineTransformMakeScale(.6f, .6f);

UISegmentedControl的扩展，用于设置字体大小。

extension UISegmentedControl {
    @available(iOS 8.2, *)
    func setFontSize(fontSize: CGFloat) {
            let normalTextAttributes: [NSObject : AnyObject]!
            if #available(iOS 9.0, *) {
                normalTextAttributes = [
                    NSFontAttributeName: UIFont.monospacedDigitSystemFontOfSize(fontSize, weight: UIFontWeightRegular)
                ]
            } else {
                normalTextAttributes = [
                    NSFontAttributeName: UIFont.systemFontOfSize(fontSize, weight: UIFontWeightRegular)
                ]
            }

        self.setTitleTextAttributes(normalTextAttributes, forState: .Normal)
    }
 }

C# / Xamarin：

segment.SetTitleTextAttributes(new UITextAttributes { 
    Font = UIFont.SystemFontOfSize(font_size) }, UIControlState.Normal);

2021年的正确答案。语法改变了。

12岁的答案(甚至是对它的编辑)是坏的。

它只是:

let _font = UIFont.systemFont(ofSize: 10)
UISegmentedControl.appearance()
 .setTitleTextAttributes([NSAttributedString.Key.font: _font], for: .normal)

你很可能会想要正确地改变高度，而你在它:

import UIKit

class SmallerSegmentedControl: UISegmentedControl {

    override init(frame: CGRect) {
        super.init(frame: frame)
        common()
    }

    required init?(coder aDecoder: NSCoder) {
        super.init(coder: aDecoder)
        common()
    }

    func common() {
        let _font = UIFont.systemFont(ofSize: 10)
        UISegmentedControl.appearance()
         .setTitleTextAttributes([NSAttributedString.Key.font: _font], for: .normal)
    }

    override var intrinsicContentSize:CGSize {
        var s = super.intrinsicContentSize
        s.height = 24
        return s
    }

}

丹尼尔指给我正确的路。我是这样用的-

float scaleFactor = 0.8f;

UISegmentedControl *segmentedControl = [[UISegmentedControl alloc]
initWithFrame:CGRectMake(10, 70, 300/scaleFactor,35)];

[segmentedControl insertSegmentWithTitle:@"..." atIndex:0 animated:NO];
[segmentedControl insertSegmentWithTitle:@"..." atIndex:1 animated:NO];
[segmentedControl insertSegmentWithTitle:@"..." atIndex:2 animated:NO];

segmentedControl.transform = CGAffineTransformMakeScale(scaleFactor, 1);
CGPoint segmentedControlCenter = segmentedControl.center;
segmentedControlCenter.x = self.center.x;
segmentedControl.center = segmentedControlCenter;