参见http://jsbin.com/ApuJOSA/1/edit?html,output上的演示。

  function mousePositionOnCanvas(e) {
      var el=e.target, c=el;
      var scaleX = c.width/c.offsetWidth || 1;
      var scaleY = c.height/c.offsetHeight || 1;

      if (!isNaN(e.offsetX)) 
          return { x:e.offsetX*scaleX, y:e.offsetY*scaleY };

      var x=e.pageX, y=e.pageY;
      do {
        x -= el.offsetLeft;
        y -= el.offsetTop;
        el = el.offsetParent;
      } while (el);
      return { x: x*scaleX, y: y*scaleY };
  }

更新(5/5/16):应该使用patriques的答案，因为它既简单又可靠。

Since the canvas isn't always styled relative to the entire page, the canvas.offsetLeft/Top doesn't always return what you need. It will return the number of pixels it is offset relative to its offsetParent element, which can be something like a div element containing the canvas with a position: relative style applied. To account for this you need to loop through the chain of offsetParents, beginning with the canvas element itself. This code works perfectly for me, tested in Firefox and Safari but should work for all.

function relMouseCoords(event){
    var totalOffsetX = 0;
    var totalOffsetY = 0;
    var canvasX = 0;
    var canvasY = 0;
    var currentElement = this;

    do{
        totalOffsetX += currentElement.offsetLeft - currentElement.scrollLeft;
        totalOffsetY += currentElement.offsetTop - currentElement.scrollTop;
    }
    while(currentElement = currentElement.offsetParent)

    canvasX = event.pageX - totalOffsetX;
    canvasY = event.pageY - totalOffsetY;

    return {x:canvasX, y:canvasY}
}
HTMLCanvasElement.prototype.relMouseCoords = relMouseCoords;

最后一行可以方便地获取相对于canvas元素的鼠标坐标。要得到有用的坐标只需要

coords = canvas.relMouseCoords(event);
canvasX = coords.x;
canvasY = coords.y;

我做了一个完整的演示，可以在每个浏览器中使用这个问题的解决方案的完整源代码:在Javascript中单击Canvas的鼠标坐标。要尝试演示，复制代码并将其粘贴到文本编辑器中。然后将其保存为example.html，最后用浏览器打开该文件。

你可以这样做:

var canvas = yourCanvasElement;
var mouseX = (event.clientX - (canvas.offsetLeft - canvas.scrollLeft)) - 2;
var mouseY = (event.clientY - (canvas.offsetTop - canvas.scrollTop)) - 2;

这将为您提供鼠标指针的确切位置。

根据最新的Quirksmode，所有主流浏览器都支持clientX和clientY方法。 所以，它开始了-在滚动条页面上的滚动div中工作的良好工作代码:

function getCursorPosition(canvas, event) {
var x, y;

canoffset = $(canvas).offset();
x = event.clientX + document.body.scrollLeft + document.documentElement.scrollLeft - Math.floor(canoffset.left);
y = event.clientY + document.body.scrollTop + document.documentElement.scrollTop - Math.floor(canoffset.top) + 1;

return [x,y];
}

这也需要jQuery $(canvas).offset()。

这是一个非常好的教程-

http://www.html5canvastutorials.com/advanced/html5-canvas-mouse-coordinates/

 <canvas id="myCanvas" width="578" height="200"></canvas>
<script>
  function writeMessage(canvas, message) {
    var context = canvas.getContext('2d');
    context.clearRect(0, 0, canvas.width, canvas.height);
    context.font = '18pt Calibri';
    context.fillStyle = 'black';
    context.fillText(message, 10, 25);
  }
  function getMousePos(canvas, evt) {
    var rect = canvas.getBoundingClientRect();
    return {
      x: evt.clientX - rect.left,
      y: evt.clientY - rect.top
    };
  }
  var canvas = document.getElementById('myCanvas');
  var context = canvas.getContext('2d');

  canvas.addEventListener('mousemove', function(evt) {
    var mousePos = getMousePos(canvas, evt);
    var message = 'Mouse position: ' + mousePos.x + ',' + mousePos.y;
    writeMessage(canvas, message);
  }, false);

希望这能有所帮助!