正如您在Tim Golden的文章(由Horst Gutmann指出)中看到的，WIN32相对复杂，它监视目录，而不是单个文件。

我建议你研究一下IronPython，它是一个。net python实现。 在IronPython中，你可以使用所有的。net功能——包括

System.IO.FileSystemWatcher

它用一个简单的Event接口处理单个文件。

最简单的解决方案是在间隔之后获取同一个文件的两个实例并进行比较。你可以试试这样的东西

    while True:
        # Capturing the two instances models.py after certain interval of time
        print("Looking for changes in " + app_name.capitalize() + " models.py\nPress 'CTRL + C' to stop the program")
        with open(app_name.capitalize() + '/filename', 'r+') as app_models_file:
            filename_content = app_models_file.read()
        time.sleep(5)
        with open(app_name.capitalize() + '/filename', 'r+') as app_models_file_1:
            filename_content_1 = app_models_file_1.read()
        # Comparing models.py after certain interval of time
        if filename_content == filename_content_1:
            pass
        else:
            print("You made a change in " + app_name.capitalize() + " filename.\n")
            cmd = str(input("Do something with the file?(y/n):"))
            if cmd == 'y':
                # Do Something
            elif cmd == 'n':
                # pass or do something
            else:
                print("Invalid input")

似乎没有人张贴fswatch。它是一个跨平台的文件系统监视器。只要安装它，运行它，并按照提示。

我在python和golang程序中使用过它，它只是工作。

如果您想要一个多平台解决方案，那么请检查QFileSystemWatcher。 下面是一个示例代码(未消毒):

from PyQt4 import QtCore

@QtCore.pyqtSlot(str)
def directory_changed(path):
    print('Directory Changed!!!')

@QtCore.pyqtSlot(str)
def file_changed(path):
    print('File Changed!!!')

fs_watcher = QtCore.QFileSystemWatcher(['/path/to/files_1', '/path/to/files_2', '/path/to/files_3'])

fs_watcher.connect(fs_watcher, QtCore.SIGNAL('directoryChanged(QString)'), directory_changed)
fs_watcher.connect(fs_watcher, QtCore.SIGNAL('fileChanged(QString)'), file_changed)

我会尝试这样的方法。

    try:
            f = open(filePath)
    except IOError:
            print "No such file: %s" % filePath
            raw_input("Press Enter to close window")
    try:
            lines = f.readlines()
            while True:
                    line = f.readline()
                    try:
                            if not line:
                                    time.sleep(1)
                            else:
                                    functionThatAnalisesTheLine(line)
                    except Exception, e:
                            # handle the exception somehow (for example, log the trace) and raise the same exception again
                            raw_input("Press Enter to close window")
                            raise e
    finally:
            f.close()

循环检查自上次读取文件以来是否有新的行——如果有，则将其读取并传递给functionThatAnalisesTheLine函数。如果不是，脚本等待1秒并重试该进程。

为了用轮询和最小依赖来观察单个文件，下面是一个完整的例子，基于Deestan的回答(上面):

import os
import sys 
import time

class Watcher(object):
    running = True
    refresh_delay_secs = 1

    # Constructor
    def __init__(self, watch_file, call_func_on_change=None, *args, **kwargs):
        self._cached_stamp = 0
        self.filename = watch_file
        self.call_func_on_change = call_func_on_change
        self.args = args
        self.kwargs = kwargs

    # Look for changes
    def look(self):
        stamp = os.stat(self.filename).st_mtime
        if stamp != self._cached_stamp:
            self._cached_stamp = stamp
            # File has changed, so do something...
            print('File changed')
            if self.call_func_on_change is not None:
                self.call_func_on_change(*self.args, **self.kwargs)

    # Keep watching in a loop        
    def watch(self):
        while self.running: 
            try: 
                # Look for changes
                time.sleep(self.refresh_delay_secs) 
                self.look() 
            except KeyboardInterrupt: 
                print('\nDone') 
                break 
            except FileNotFoundError:
                # Action on file not found
                pass
            except: 
                print('Unhandled error: %s' % sys.exc_info()[0])

# Call this function each time a change happens
def custom_action(text):
    print(text)

watch_file = 'my_file.txt'

# watcher = Watcher(watch_file)  # simple
watcher = Watcher(watch_file, custom_action, text='yes, changed')  # also call custom action function
watcher.watch()  # start the watch going