我对Mark Byers给出的代码做了一些修改。如果您有空目录，下面的函数也会添加它们。示例应该更清楚添加到zip的路径是什么。

#!/usr/bin/env python
import os
import zipfile

def addDirToZip(zipHandle, path, basePath=""):
    """
    Adding directory given by \a path to opened zip file \a zipHandle

    @param basePath path that will be removed from \a path when adding to archive

    Examples:
        # add whole "dir" to "test.zip" (when you open "test.zip" you will see only "dir")
        zipHandle = zipfile.ZipFile('test.zip', 'w')
        addDirToZip(zipHandle, 'dir')
        zipHandle.close()

        # add contents of "dir" to "test.zip" (when you open "test.zip" you will see only it's contents)
        zipHandle = zipfile.ZipFile('test.zip', 'w')
        addDirToZip(zipHandle, 'dir', 'dir')
        zipHandle.close()

        # add contents of "dir/subdir" to "test.zip" (when you open "test.zip" you will see only contents of "subdir")
        zipHandle = zipfile.ZipFile('test.zip', 'w')
        addDirToZip(zipHandle, 'dir/subdir', 'dir/subdir')
        zipHandle.close()

        # add whole "dir/subdir" to "test.zip" (when you open "test.zip" you will see only "subdir")
        zipHandle = zipfile.ZipFile('test.zip', 'w')
        addDirToZip(zipHandle, 'dir/subdir', 'dir')
        zipHandle.close()

        # add whole "dir/subdir" with full path to "test.zip" (when you open "test.zip" you will see only "dir" and inside it only "subdir")
        zipHandle = zipfile.ZipFile('test.zip', 'w')
        addDirToZip(zipHandle, 'dir/subdir')
        zipHandle.close()

        # add whole "dir" and "otherDir" (with full path) to "test.zip" (when you open "test.zip" you will see only "dir" and "otherDir")
        zipHandle = zipfile.ZipFile('test.zip', 'w')
        addDirToZip(zipHandle, 'dir')
        addDirToZip(zipHandle, 'otherDir')
        zipHandle.close()
    """
    basePath = basePath.rstrip("\\/") + ""
    basePath = basePath.rstrip("\\/")
    for root, dirs, files in os.walk(path):
        # add dir itself (needed for empty dirs
        zipHandle.write(os.path.join(root, "."))
        # add files
        for file in files:
            filePath = os.path.join(root, file)
            inZipPath = filePath.replace(basePath, "", 1).lstrip("\\/")
            #print filePath + " , " + inZipPath
            zipHandle.write(filePath, inZipPath)

以上是一个简单的函数，适用于简单的情况。你可以在我的Gist中找到更优雅的课程：https://gist.github.com/Eccenux/17526123107ca0ac28e6

现代Python（3.6+）使用pathlib模块对路径进行类似OOP的简洁处理，使用pathlib.Path.rglob（）进行递归globing。据我所知，这相当于乔治·V·莱利的回答：压缩压缩，最顶层的元素是目录，保持空目录，使用相对路径。

from pathlib import Path
from zipfile import ZIP_DEFLATED, ZipFile

from os import PathLike
from typing import Union


def zip_dir(zip_name: str, source_dir: Union[str, PathLike]):
    src_path = Path(source_dir).expanduser().resolve(strict=True)
    with ZipFile(zip_name, 'w', ZIP_DEFLATED) as zf:
        for file in src_path.rglob('*'):
            zf.write(file, file.relative_to(src_path.parent))

注意：如可选类型提示所示，zip_name不能是Path对象（将在3.6.2+中修复）。

下面是Nux给出的答案的一个变体，对我有用：

def WriteDirectoryToZipFile( zipHandle, srcPath, zipLocalPath = "", zipOperation = zipfile.ZIP_DEFLATED ):
    basePath = os.path.split( srcPath )[ 0 ]
    for root, dirs, files in os.walk( srcPath ):
        p = os.path.join( zipLocalPath, root [ ( len( basePath ) + 1 ) : ] )
        # add dir
        zipHandle.write( root, p, zipOperation )
        # add files
        for f in files:
            filePath = os.path.join( root, f )
            fileInZipPath = os.path.join( p, f )
            zipHandle.write( filePath, fileInZipPath, zipOperation )

试试下面的一个。它对我有用。

import zipfile, os
zipf = "compress.zip"  
def main():
    directory = r"Filepath"
    toZip(directory)
def toZip(directory):
    zippedHelp = zipfile.ZipFile(zipf, "w", compression=zipfile.ZIP_DEFLATED )

    list = os.listdir(directory)
    for file_list in list:
        file_name = os.path.join(directory,file_list)

        if os.path.isfile(file_name):
            print file_name
            zippedHelp.write(file_name)
        else:
            addFolderToZip(zippedHelp,file_list,directory)
            print "---------------Directory Found-----------------------"
    zippedHelp.close()

def addFolderToZip(zippedHelp,folder,directory):
    path=os.path.join(directory,folder)
    print path
    file_list=os.listdir(path)
    for file_name in file_list:
        file_path=os.path.join(path,file_name)
        if os.path.isfile(file_path):
            zippedHelp.write(file_path)
        elif os.path.isdir(file_name):
            print "------------------sub directory found--------------------"
            addFolderToZip(zippedHelp,file_name,path)


if __name__=="__main__":
    main()

这是一种现代方法，使用pathlib和上下文管理器。将文件直接放在zip文件中，而不是放在子文件夹中。

def zip_dir(filename: str, dir_to_zip: pathlib.Path):
    with zipfile.ZipFile(filename, 'w', zipfile.ZIP_DEFLATED) as zipf:
        # Use glob instead of iterdir(), to cover all subdirectories.
        for directory in dir_to_zip.glob('**'):
            for file in directory.iterdir():
                if not file.is_file():
                    continue
                # Strip the first component, so we don't create an uneeded subdirectory
                # containing everything.
                zip_path = pathlib.Path(*file.parts[1:])
                # Use a string, since zipfile doesn't support pathlib  directly.
                zipf.write(str(file), str(zip_path))

前面的答案完全忽略了一点，即当您在Windows上运行代码时，使用os.path.join（）可以很容易地返回POSIX不兼容的路径。当使用Linux上的任何常用归档软件处理文件时，生成的归档文件将包含名称中带有反斜杠的文件，这不是您想要的。请改用path.as_posix（）作为arcname参数！

import zipfile
from pathlib import Path
with zipfile.ZipFile("archive.zip", "w", zipfile.ZIP_DEFLATED) as zf:
    for path in Path("include_all_of_this_folder").rglob("*"):
        zf.write(path, path.as_posix())