在3楼看到答案后，我试图弄清楚设置TableView和TableViewCell之间的分隔符是什么关系，并做了一些测试。以下是我的结论:

we can consider that setting the cell's separator to zero has to move the separator in two steps: first step is to set cell's separatorinset to zero. second step is to set cell's marginlayout to zero. set the TableView's separatorinset and marginlayout can affect the Cell's separatorinset. However, from the test, I find that the TableView's separatorinset seem to be useless, TableView's marginlayout can actually affect cell's marginlayout. set Cell's PreservesSuperviewLayoutMargins = false, can cut off TableView's marginlayout effect on Cells. one of the solutions: func tableView(tableView: UITableView, cellForRowAtIndexPath indexPath: NSIndexPath) -> UITableViewCell { var cell = UITableViewCell() cell.preservesSuperviewLayoutMargins = false cell.separatorInset = UIEdgeInsetsZero cell.layoutMargins = UIEdgeInsetsZero return cell }

-(UITableViewCell *)tableView:(UITableView *)tableView cellForRowAtIndexPath:(NSIndexPath *)indexPath {
        // ... Get the cell
        cell.separatorInset = UIEdgeInsetsMake(0.f, 20.f, 0.f, [UIScreen mainScreen].bounds.size.width - 20);
        // others
        return cell;
}

对于要隐藏分隔符的任何特定单元格。

对我来说，除了这个解决方案(Swift 3.0)之外，其他方法都不起作用:

extension UIColor {
    static func colorWith(hex:String, alpha: CGFloat) -> UIColor {
        var cString = hex.trimmingCharacters(in: .whitespacesAndNewlines).uppercased()

        if cString.hasPrefix("#") {
            cString.remove(at: cString.startIndex)
        }

        if cString.characters.count != 6 {
            return UIColor.gray
        }

        var rgbValue:UInt32 = 0
        Scanner(string: cString).scanHexInt32(&rgbValue)

        return UIColor(red:   CGFloat((rgbValue & 0xFF0000) >> 16) / 255.0,
                       green: CGFloat((rgbValue & 0x00FF00) >> 8)  / 255.0,
                       blue:  CGFloat( rgbValue & 0x0000FF)        / 255.0,
                       alpha: alpha)
    }
}

func tableView(_ tableView: UITableView, cellForRowAt indexPath: IndexPath) -> UITableViewCell {
    let cell = tableView.dequeueReusableCell(withIdentifier: cellReuseIdendifier, for: indexPath)

    cell.backgroundColor = UIColor.colorWith(hex: "c8c7cc", alpha: 1) // same color of line separator

    return cell
}

至于cdstamper建议的表格视图，在单元格的layoutSubview方法中添加以下行对我来说是可行的。

- (void)layoutSubviews 
{
    [super layoutSubviews];

    if ([self respondsToSelector:@selector(setSeparatorInset:)])
                [self setSeparatorInset:UIEdgeInsetsZero];

        if ([self respondsToSelector:@selector(setPreservesSuperviewLayoutMargins:)])
        {
            [self setPreservesSuperviewLayoutMargins:NO];;
        }

        if ([self respondsToSelector:@selector(setLayoutMargins:)]) 
        {
            [self setLayoutMargins:UIEdgeInsetsZero];
        }
}

在Swift中你可以使用这个

    cell.selectionStyle = UITableViewCellSelectionStyle.None
    cell.preservesSuperviewLayoutMargins = false
    cell.separatorInset = UIEdgeInsetsZero
    cell.layoutMargins = UIEdgeInsetsZero

对我来说，简单的线条就够了

cell.layoutMargins = UIEdgeInsetsZero