非常简单的解决方法

if(UI_USER_INTERFACE_IDIOM() == UIUserInterfaceIdiomPhone)
{
    CGSize result = [[UIScreen mainScreen] bounds].size;
    if(result.height == 480)
    {
        // iPhone Classic
    }
    if(result.height == 568)
    {
        // iPhone 5
    }
}

通过这种方式，您可以检测设备系列。

    #import <sys/utsname.h>
    NSString* deviceName()
    {
        struct utsname systemInformation;
        uname(&systemInformation);
        NSString *result = [NSString stringWithCString:systemInformation.machine
                                              encoding:NSUTF8StringEncoding];
        return result;
    }

    #define isIPhone5  [deviceName() rangeOfString:@"iPhone5,"].location != NSNotFound
    #define isIPhone5S [deviceName() rangeOfString:@"iPhone6,"].location != NSNotFound

这是我们的代码，在ios7/ios8上测试通过，适用于iphone4、iphone5、ipad、iphone6、iphone6p，无论在设备上还是模拟器上:

#define IS_IPAD (UI_USER_INTERFACE_IDIOM() == UIUserInterfaceIdiomPad)
#define IS_IPHONE (UI_USER_INTERFACE_IDIOM() == UIUserInterfaceIdiomPhone) // iPhone and       iPod touch style UI

#define IS_IPHONE_5_IOS7 (IS_IPHONE && [[UIScreen mainScreen] bounds].size.height == 568.0f)
#define IS_IPHONE_6_IOS7 (IS_IPHONE && [[UIScreen mainScreen] bounds].size.height == 667.0f)
#define IS_IPHONE_6P_IOS7 (IS_IPHONE && [[UIScreen mainScreen] bounds].size.height == 736.0f)
#define IS_IPHONE_4_AND_OLDER_IOS7 (IS_IPHONE && [[UIScreen mainScreen] bounds].size.height < 568.0f)

#define IS_IPHONE_5_IOS8 (IS_IPHONE && ([[UIScreen mainScreen] nativeBounds].size.height/[[UIScreen mainScreen] nativeScale]) == 568.0f)
#define IS_IPHONE_6_IOS8 (IS_IPHONE && ([[UIScreen mainScreen] nativeBounds].size.height/[[UIScreen mainScreen] nativeScale]) == 667.0f)
#define IS_IPHONE_6P_IOS8 (IS_IPHONE && ([[UIScreen mainScreen] nativeBounds].size.height/[[UIScreen mainScreen] nativeScale]) == 736.0f)
#define IS_IPHONE_4_AND_OLDER_IOS8 (IS_IPHONE && ([[UIScreen mainScreen] nativeBounds].size.height/[[UIScreen mainScreen] nativeScale]) < 568.0f)

#define IS_IPHONE_5 ( ( [ [ UIScreen mainScreen ] respondsToSelector: @selector( nativeBounds ) ] ) ? IS_IPHONE_5_IOS8 : IS_IPHONE_5_IOS7 )
#define IS_IPHONE_6 ( ( [ [ UIScreen mainScreen ] respondsToSelector: @selector( nativeBounds ) ] ) ? IS_IPHONE_6_IOS8 : IS_IPHONE_6_IOS7 )
#define IS_IPHONE_6P ( ( [ [ UIScreen mainScreen ] respondsToSelector: @selector( nativeBounds ) ] ) ? IS_IPHONE_6P_IOS8 : IS_IPHONE_6P_IOS7 )
#define IS_IPHONE_4_AND_OLDER ( ( [ [ UIScreen mainScreen ] respondsToSelector: @selector( nativeBounds ) ] ) ? IS_IPHONE_4_AND_OLDER_IOS8 : IS_IPHONE_4_AND_OLDER_IOS7 )

我用hfossli的答案翻译给了Swift

let IS_IPAD = UIDevice.currentDevice().userInterfaceIdiom == .Pad
let IS_IPHONE = UIDevice.currentDevice().userInterfaceIdiom == .Phone
let IS_RETINA = UIScreen.mainScreen().scale >= 2.0

let SCREEN_WIDTH = UIScreen.mainScreen().bounds.size.width
let SCREEN_HEIGHT = UIScreen.mainScreen().bounds.size.height
let SCREEN_MAX_LENGTH = max(SCREEN_WIDTH, SCREEN_HEIGHT)
let SCREEN_MIN_LENGTH = min(SCREEN_WIDTH, SCREEN_HEIGHT)

let IS_IPHONE_4_OR_LESS = (IS_IPHONE && SCREEN_MAX_LENGTH < 568.0)
let IS_IPHONE_5 = (IS_IPHONE && SCREEN_MAX_LENGTH == 568.0)
let IS_IPHONE_6 = (IS_IPHONE && SCREEN_MAX_LENGTH == 667.0)
let IS_IPHONE_6P = (IS_IPHONE && SCREEN_MAX_LENGTH == 736.0)

借用Samrat Mazumdar的回答，这里有一个估算设备屏幕大小的简单方法。它适用于最新的设备，但在未来的设备上可能会失败(正如所有猜测的方法一样)。如果设备正在镜像，它也会混淆(返回设备的屏幕大小，而不是镜像的屏幕大小)

#define SCREEN_SIZE_IPHONE_CLASSIC 3.5
#define SCREEN_SIZE_IPHONE_TALL 4.0
#define SCREEN_SIZE_IPAD_CLASSIC 9.7

+ (CGFloat)screenPhysicalSize
{
    if(UI_USER_INTERFACE_IDIOM() == UIUserInterfaceIdiomPhone)
    {
        CGSize result = [[UIScreen mainScreen] bounds].size;
        if (result.height < 500)
            return SCREEN_SIZE_IPHONE_CLASSIC;  // iPhone 4S / 4th Gen iPod Touch or earlier
        else
            return SCREEN_SIZE_IPHONE_TALL;  // iPhone 5
    }
    else
    {
        return SCREEN_SIZE_IPAD_CLASSIC; // iPad
    }
} 

Add a 'New Swift File'-> AppDelegateEx.swift add an extension to AppDelegate import UIKit extension AppDelegate { class func isIPhone5 () -> Bool{ return max(UIScreen.mainScreen().bounds.width, UIScreen.mainScreen().bounds.height) == 568.0 } class func isIPhone6 () -> Bool { return max(UIScreen.mainScreen().bounds.width, UIScreen.mainScreen().bounds.height) == 667.0 } class func isIPhone6Plus () -> Bool { return max(UIScreen.mainScreen().bounds.width, UIScreen.mainScreen().bounds.height) == 736.0 } } usage: if AppDelegate.isIPhone5() { collectionViewTopConstraint.constant = 2 }else if AppDelegate.isIPhone6() { collectionViewTopConstraint.constant = 20 }