下面是Kender代码的简化版本，它似乎做了同样的技巧，并且没有导入整个文件:

# Check file for new data.

import time

f = open(r'c:\temp\test.txt', 'r')

while True:

    line = f.readline()
    if not line:
        time.sleep(1)
        print 'Nothing New'
    else:
        print 'Call Function: ', line

正如您在Tim Golden的文章(由Horst Gutmann指出)中看到的，WIN32相对复杂，它监视目录，而不是单个文件。

我建议你研究一下IronPython，它是一个。net python实现。 在IronPython中，你可以使用所有的。net功能——包括

System.IO.FileSystemWatcher

它用一个简单的Event接口处理单个文件。

最简单的解决方案是在间隔之后获取同一个文件的两个实例并进行比较。你可以试试这样的东西

    while True:
        # Capturing the two instances models.py after certain interval of time
        print("Looking for changes in " + app_name.capitalize() + " models.py\nPress 'CTRL + C' to stop the program")
        with open(app_name.capitalize() + '/filename', 'r+') as app_models_file:
            filename_content = app_models_file.read()
        time.sleep(5)
        with open(app_name.capitalize() + '/filename', 'r+') as app_models_file_1:
            filename_content_1 = app_models_file_1.read()
        # Comparing models.py after certain interval of time
        if filename_content == filename_content_1:
            pass
        else:
            print("You made a change in " + app_name.capitalize() + " filename.\n")
            cmd = str(input("Do something with the file?(y/n):"))
            if cmd == 'y':
                # Do Something
            elif cmd == 'n':
                # pass or do something
            else:
                print("Invalid input")

如果轮询对您来说足够好，我只观察“修改的时间”文件统计是否发生变化。阅读方法:

os.stat(filename).st_mtime

(还要注意，Windows本机更改事件解决方案并不在所有情况下都有效，例如在网络驱动器上。)

import os

class Monkey(object):
    def __init__(self):
        self._cached_stamp = 0
        self.filename = '/path/to/file'

    def ook(self):
        stamp = os.stat(self.filename).st_mtime
        if stamp != self._cached_stamp:
            self._cached_stamp = stamp
            # File has changed, so do something...

如果您想要一个多平台解决方案，那么请检查QFileSystemWatcher。 下面是一个示例代码(未消毒):

from PyQt4 import QtCore

@QtCore.pyqtSlot(str)
def directory_changed(path):
    print('Directory Changed!!!')

@QtCore.pyqtSlot(str)
def file_changed(path):
    print('File Changed!!!')

fs_watcher = QtCore.QFileSystemWatcher(['/path/to/files_1', '/path/to/files_2', '/path/to/files_3'])

fs_watcher.connect(fs_watcher, QtCore.SIGNAL('directoryChanged(QString)'), directory_changed)
fs_watcher.connect(fs_watcher, QtCore.SIGNAL('fileChanged(QString)'), file_changed)

下面是一个示例，用于观察每秒写入不超过一行但通常要少得多的输入文件。目标是将最后一行(最近的写入)追加到指定的输出文件。我从我的一个项目中复制了这个，只是删除了所有不相关的行。你必须填写或修改缺失的符号。

from PyQt5.QtCore import QFileSystemWatcher, QSettings, QThread
from ui_main_window import Ui_MainWindow   # Qt Creator gen'd 

class MainWindow(QMainWindow, Ui_MainWindow):
    def __init__(self, parent=None):
        QMainWindow.__init__(self, parent)
        Ui_MainWindow.__init__(self)
        self._fileWatcher = QFileSystemWatcher()
        self._fileWatcher.fileChanged.connect(self.fileChanged)

    def fileChanged(self, filepath):
        QThread.msleep(300)    # Reqd on some machines, give chance for write to complete
        # ^^ About to test this, may need more sophisticated solution
        with open(filepath) as file:
            lastLine = list(file)[-1]
        destPath = self._filemap[filepath]['dest file']
        with open(destPath, 'a') as out_file:               # a= append
            out_file.writelines([lastLine])

当然，并不是严格要求包含QMainWindow类。您可以单独使用QFileSystemWatcher。