另一种解决方案可能与HTMLIFrameElement接口的情况类似。如果我们知道在另一个模块中有它的实现，我们可以通过在接口旁边创建一个对象来声明一个同名的变量。

declare var HTMLIFrameElement: {
    prototype: HTMLIFrameElement;
    new(): HTMLIFrameElement;
};

在这种情况下

interface A {
    member:string;
}

declare var A : {
    prototype: A;
    new(): A;
};

if(a instanceof A) alert(a.member);

应该没问题

下面是我使用类和lodash想出的解决方案:(它有效!)

// TypeChecks.ts
import _ from 'lodash';

export class BakedChecker {
    private map: Map<string, string>;

    public constructor(keys: string[], types: string[]) {
        this.map = new Map<string, string>(keys.map((k, i) => {
            return [k, types[i]];
        }));
        if (this.map.has('__optional'))
            this.map.delete('__optional');
    }

    getBakedKeys() : string[] {
        return Array.from(this.map.keys());
    }

    getBakedType(key: string) : string {
        return this.map.has(key) ? this.map.get(key) : "notfound";
    }
}

export interface ICheckerTemplate {
    __optional?: any;
    [propName: string]: any;
}

export function bakeChecker(template : ICheckerTemplate) : BakedChecker {
    let keys = _.keysIn(template);
    if ('__optional' in template) {
        keys = keys.concat(_.keysIn(template.__optional).map(k => '?' + k));
    }
    return new BakedChecker(keys, keys.map(k => {
        const path = k.startsWith('?') ? '__optional.' + k.substr(1) : k;
        const val = _.get(template, path);
        if (typeof val === 'object') return val;
        return typeof val;
    }));
}

export default function checkType<T>(obj: any, template: BakedChecker) : obj is T {
    const o_keys = _.keysIn(obj);
    const t_keys = _.difference(template.getBakedKeys(), ['__optional']);
    return t_keys.every(tk => {
        if (tk.startsWith('?')) {
            const ak = tk.substr(1);
            if (o_keys.includes(ak)) {
                const tt = template.getBakedType(tk);
                if (typeof tt === 'string')
                    return typeof _.get(obj, ak) === tt;
                else {
                    return checkType<any>(_.get(obj, ak), tt);
                }
            }
            return true;
        }
        else {
            if (o_keys.includes(tk)) {
                const tt = template.getBakedType(tk);
                if (typeof tt === 'string')
                    return typeof _.get(obj, tk) === tt;
                else {
                    return checkType<any>(_.get(obj, tk), tt);
                }
            }
            return false;
        }
    });
}

自定义类:

// MyClasses.ts

import checkType, { bakeChecker } from './TypeChecks';

class Foo {
    a?: string;
    b: boolean;
    c: number;

    public static _checker = bakeChecker({
        __optional: {
            a: ""
        },
        b: false,
        c: 0
    });
}

class Bar {
    my_string?: string;
    another_string: string;
    foo?: Foo;

    public static _checker = bakeChecker({
        __optional: {
            my_string: "",
            foo: Foo._checker
        },
        another_string: ""
    });
}

在运行时检查类型:

if (checkType<Bar>(foreign_object, Bar._checker)) { ... }

这里还有另一个选项:模块ts-interface-builder提供了一个构建时工具，可以将TypeScript接口转换为运行时描述符，ts-interface-checker可以检查对象是否满足它。

对于OP的例子，

interface A {
  member: string;
}

首先运行ts-interface-builder，它会生成一个带有描述符(比如foo-ti)的新简洁文件。Ts，你可以这样用:

import fooDesc from './foo-ti.ts';
import {createCheckers} from "ts-interface-checker";
const {A} = createCheckers(fooDesc);

A.check({member: "hello"});           // OK
A.check({member: 17});                // Fails with ".member is not a string" 

你可以创建一个单行类型保护函数:

function isA(value: any): value is A { return A.test(value); }

使用字符串文字是很困难的，因为如果你想重构你的方法或接口名称，那么你的IDE可能不重构这些字符串文字。 我为您提供我的解决方案，如果在接口中至少有一个方法

export class SomeObject implements interfaceA {
  public methodFromA() {}
}

export interface interfaceA {
  methodFromA();
}

检查object是否为interface类型:

const obj = new SomeObject();
const objAsAny = obj as any;
const objAsInterfaceA = objAsAny as interfaceA;
const isObjOfTypeInterfaceA = objAsInterfaceA.methodFromA != null;
console.log(isObjOfTypeInterfaceA)

注意:即使我们删除了'implements interfaceA'，我们也会得到true，因为SomeObject类中仍然存在该方法

TypeGuards

interface MyInterfaced {
    x: number
}

function isMyInterfaced(arg: any): arg is MyInterfaced {
    return arg.x !== undefined;
}

if (isMyInterfaced(obj)) {
    (obj as MyInterfaced ).x;
}

在我看来，这是最好的方法;在接口上附加一个“Fubber”符号。它的编写速度要快得多，对于JavaScript引擎来说，它比类型保护快得多，它支持接口的继承，如果你需要的话，它使类型保护易于编写。

这就是ES6有符号的目的。

接口

// Notice there is no naming conflict, because interfaces are a *type*
export const IAnimal = Symbol("IAnimal"); 
export interface IAnimal {
  [IAnimal]: boolean; // the fubber
}

export const IDog = Symbol("IDog");
export interface IDog extends IAnimal {
  [IDog]: boolean;
}

export const IHound = Symbol("IDog");
export interface IHound extends IDog {
  // The fubber can also be typed as only 'true'; meaning it can't be disabled.
  [IDog]: true;
  [IHound]: boolean;
}

类

import { IDog, IAnimal } from './interfaces';
class Dog implements IDog {
  // Multiple fubbers to handle inheritance:
  [IAnimal] = true;
  [IDog] = true;
}

class Hound extends Dog implements IHound {
  [IHound] = true;
}

测试

如果你想帮助TypeScript编译器，这段代码可以放在类型保护中。

import { IDog, IAnimal } from './interfaces';

let dog = new Dog();

if (dog instanceof Hound || dog[IHound]) {
  // false
}
if (dog[IAnimal]?) {
  // true
}

let houndDog = new Hound();

if (houndDog[IDog]) {
  // true
}

if (dog[IDog]?) {
  // it definitely is a dog
}