这是我对这个问题的解决办法。我把它用在聊天机器人上，一次替换不同的单词。

def mass_replace(text, dct):
    new_string = ""
    old_string = text
    while len(old_string) > 0:
        s = ""
        sk = ""
        for k in dct.keys():
            if old_string.startswith(k):
                s = dct[k]
                sk = k
        if s:
            new_string+=s
            old_string = old_string[len(sk):]
        else:
            new_string+=old_string[0]
            old_string = old_string[1:]
    return new_string

print mass_replace("The dog hunts the cat", {"dog":"cat", "cat":"dog"})

这就成了猫捉狗

注意:测试你的案例，见注释。

这里有一个例子，它在长弦上更有效，有许多小的替换。

source = "Here is foo, it does moo!"

replacements = {
    'is': 'was', # replace 'is' with 'was'
    'does': 'did',
    '!': '?'
}

def replace(source, replacements):
    finder = re.compile("|".join(re.escape(k) for k in replacements.keys())) # matches every string we want replaced
    result = []
    pos = 0
    while True:
        match = finder.search(source, pos)
        if match:
            # cut off the part up until match
            result.append(source[pos : match.start()])
            # cut off the matched part and replace it in place
            result.append(replacements[source[match.start() : match.end()]])
            pos = match.end()
        else:
            # the rest after the last match
            result.append(source[pos:])
            break
    return "".join(result)

print replace(source, replacements)

关键是要避免长字符串的多次连接。我们将源字符串切成片段，在我们形成列表时替换一些片段，然后将整个字符串连接回字符串。

sentence='its some sentence with a something text'

def replaceAll(f,Array1,Array2):
    if len(Array1)==len(Array2):
        for x in range(len(Array1)):
            return f.replace(Array1[x],Array2[x])

newSentence=replaceAll(sentence,['a','sentence','something'],['another','sentence','something something'])

print(newSentence)

我的方法是首先将字符串标记化，然后决定每个标记是否包含它。

潜在地，如果我们可以假设一个hashmap/set的O(1)查找，可能会更好:

remove_words = {"we", "this"}
target_sent = "we should modify this string"
target_sent_words = target_sent.split()
filtered_sent = " ".join(list(filter(lambda word: word not in remove_words, target_sent_words)))

Filtered_sent现在是'应该修改字符串'

这是我的0.02美元。它基于Andrew Clark的答案，只是更清楚一点，它还涵盖了当一个字符串被替换为另一个字符串的子字符串时的情况(更长的字符串胜出)

def multireplace(string, replacements):
    """
    Given a string and a replacement map, it returns the replaced string.

    :param str string: string to execute replacements on
    :param dict replacements: replacement dictionary {value to find: value to replace}
    :rtype: str

    """
    # Place longer ones first to keep shorter substrings from matching
    # where the longer ones should take place
    # For instance given the replacements {'ab': 'AB', 'abc': 'ABC'} against 
    # the string 'hey abc', it should produce 'hey ABC' and not 'hey ABc'
    substrs = sorted(replacements, key=len, reverse=True)

    # Create a big OR regex that matches any of the substrings to replace
    regexp = re.compile('|'.join(map(re.escape, substrs)))

    # For each match, look up the new string in the replacements
    return regexp.sub(lambda match: replacements[match.group(0)], string)

这就是这个要点，如果你有任何建议，请随意修改。

下面是另一种使用字典的方法:

listA="The cat jumped over the house".split()
modify = {word:word for number,word in enumerate(listA)}
modify["cat"],modify["jumped"]="dog","walked"
print " ".join(modify[x] for x in listA)