我刚刚用乘数特性解决了我的问题。我不确定它是否适用于所有情况，但对我来说，它非常有效。我在Xcode 6.3供你参考。

我最后做的是:

1)首先将我的按钮放置在320px宽度的屏幕上，以我希望它在320px设备上的方式分布。

2)然后我在所有按钮的superview上添加了一个领先的空间约束。

3)然后我修改了前导空间的属性，使常量为0，乘数是x偏移量除以屏幕宽度(例如，我的第一个按钮距离左边缘8px，所以我将乘数设置为8/320)

4)那么这里重要的一步是将约束关系中的第二个Item更改为superview。尾随而不是superview.leading。这很关键，因为superview。在我的例子中，前导为0，后拖为320，所以8/320在320px设备上是8px，然后当父视图的宽度改变为640或其他什么时，视图都以相对于320px屏幕大小的宽度的比例移动。这里的数学比较容易理解。

这里还有另一个答案。我在回答一个类似的问题时看到了这个问题的链接。我没有看到任何与我类似的答案。所以我想写在这里。

  class ViewController: UIViewController {

    override func viewDidLoad() {
        super.viewDidLoad()
        view.backgroundColor = UIColor.whiteColor()
        setupViews()
    }

    var constraints: [NSLayoutConstraint] = []

    func setupViews() {

        let container1 = createButtonContainer(withButtonTitle: "Button 1")
        let container2 = createButtonContainer(withButtonTitle: "Button 2")
        let container3 = createButtonContainer(withButtonTitle: "Button 3")
        let container4 = createButtonContainer(withButtonTitle: "Button 4")

        view.addSubview(container1)
        view.addSubview(container2)
        view.addSubview(container3)
        view.addSubview(container4)

        [

            // left right alignment
            container1.leftAnchor.constraintEqualToAnchor(view.leftAnchor, constant: 20),
            container1.rightAnchor.constraintEqualToAnchor(view.rightAnchor, constant: -20),
            container2.leftAnchor.constraintEqualToAnchor(container1.leftAnchor),
            container2.rightAnchor.constraintEqualToAnchor(container1.rightAnchor),
            container3.leftAnchor.constraintEqualToAnchor(container1.leftAnchor),
            container3.rightAnchor.constraintEqualToAnchor(container1.rightAnchor),
            container4.leftAnchor.constraintEqualToAnchor(container1.leftAnchor),
            container4.rightAnchor.constraintEqualToAnchor(container1.rightAnchor),


            // place containers one after another vertically
            container1.topAnchor.constraintEqualToAnchor(view.topAnchor),
            container2.topAnchor.constraintEqualToAnchor(container1.bottomAnchor),
            container3.topAnchor.constraintEqualToAnchor(container2.bottomAnchor),
            container4.topAnchor.constraintEqualToAnchor(container3.bottomAnchor),
            container4.bottomAnchor.constraintEqualToAnchor(view.bottomAnchor),


            // container height constraints
            container2.heightAnchor.constraintEqualToAnchor(container1.heightAnchor),
            container3.heightAnchor.constraintEqualToAnchor(container1.heightAnchor),
            container4.heightAnchor.constraintEqualToAnchor(container1.heightAnchor)
            ]
            .forEach { $0.active = true }
    }


    func createButtonContainer(withButtonTitle title: String) -> UIView {
        let view = UIView(frame: .zero)
        view.translatesAutoresizingMaskIntoConstraints = false

        let button = UIButton(type: .System)
        button.translatesAutoresizingMaskIntoConstraints = false
        button.setTitle(title, forState: .Normal)
        view.addSubview(button)

        [button.centerYAnchor.constraintEqualToAnchor(view.centerYAnchor),
            button.leftAnchor.constraintEqualToAnchor(view.leftAnchor),
            button.rightAnchor.constraintEqualToAnchor(view.rightAnchor)].forEach { $0.active = true }

        return view
    }
}

同样，这也可以用iOS9 UIStackViews很容易做到。

class ViewController: UIViewController {

    override func viewDidLoad() {
        super.viewDidLoad()
        view.backgroundColor = UIColor.greenColor()
        setupViews()
    }

    var constraints: [NSLayoutConstraint] = []

    func setupViews() {

        let container1 = createButtonContainer(withButtonTitle: "Button 1")
        let container2 = createButtonContainer(withButtonTitle: "Button 2")
        let container3 = createButtonContainer(withButtonTitle: "Button 3")
        let container4 = createButtonContainer(withButtonTitle: "Button 4")

        let stackView = UIStackView(arrangedSubviews: [container1, container2, container3, container4])
        stackView.translatesAutoresizingMaskIntoConstraints = false
        stackView.axis = .Vertical
        stackView.distribution = .FillEqually
        view.addSubview(stackView)

        [stackView.topAnchor.constraintEqualToAnchor(view.topAnchor),
            stackView.bottomAnchor.constraintEqualToAnchor(view.bottomAnchor),
            stackView.leftAnchor.constraintEqualToAnchor(view.leftAnchor, constant: 20),
            stackView.rightAnchor.constraintEqualToAnchor(view.rightAnchor, constant: -20)].forEach { $0.active = true }
    }


    func createButtonContainer(withButtonTitle title: String) -> UIView {
        let button = UIButton(type: .Custom)
        button.translatesAutoresizingMaskIntoConstraints = false
        button.backgroundColor = UIColor.redColor()
        button.setTitleColor(UIColor.whiteColor(), forState: .Normal)
        button.setTitle(title, forState: .Normal)
        let buttonContainer = UIStackView(arrangedSubviews: [button])
        buttonContainer.distribution = .EqualCentering
        buttonContainer.alignment = .Center
        buttonContainer.translatesAutoresizingMaskIntoConstraints = false
        return buttonContainer
    }
}

注意，这与上面的方法完全相同。它添加了四个容器视图，这些视图都是均等填充的，每个堆栈视图都添加了一个视图，并在中间对齐。但是，这个版本的UIStackView减少了一些代码，看起来不错。

是的，你可以只在接口构建器中这样做，而不需要编写代码——需要注意的是，你是在调整标签的大小，而不是分配空白。在本例中，将标签2的X和Y对齐到父视图，使其固定在中心。然后将标签1的垂直空间设置为superview，标签2设置为standard，重复标签3。在设置标签2之后，设置标签1和3最简单的方法是调整它们的大小，直到它们断开。

这是水平显示，注意标签1和2之间的垂直空间被设置为标准:

这是竖屏版本:

我意识到，由于标签之间的标准空间和父视图的标准空间之间的差异，它们在基线之间不是绝对100%等间距的。如果这让您感到困扰，可以将大小设置为0而不是standard

Swift 3版本

let _redView = UIView()
        _redView.backgroundColor = UIColor.red
        _redView.translatesAutoresizingMaskIntoConstraints = false

        let _yellowView = UIView()
        _yellowView.backgroundColor = UIColor.yellow
        _yellowView.translatesAutoresizingMaskIntoConstraints = false

        let _blueView = UIView()
        _blueView.backgroundColor = UIColor.blue
        _blueView.translatesAutoresizingMaskIntoConstraints = false

        self.view.addSubview(_redView)
        self.view.addSubview(_yellowView)
        self.view.addSubview(_blueView)

        var views = ["_redView": _redView, "_yellowView": _yellowView, "_blueView":_blueView]

        var nslayoutConstraint_H = NSLayoutConstraint.constraints(withVisualFormat: "|->=0-[_redView(40)]->=0-[_yellowView(40)]->=0-[_blueView(40)]->=0-|", options: [.alignAllTop, .alignAllBottom], metrics: nil, views: views)
        self.view.addConstraints(nslayoutConstraint_H)

        var nslayoutConstraint_V = NSLayoutConstraint.constraints(withVisualFormat: "V:[_redView(60)]", options: NSLayoutFormatOptions.init(rawValue: 0), metrics: nil, views: views)
        self.view.addConstraints(nslayoutConstraint_V)


        let constraint_red = NSLayoutConstraint.init(item: self.view, attribute: .centerY, relatedBy: .equal, toItem: _redView, attribute: .centerY, multiplier: 1, constant: 0)
        self.view.addConstraint(constraint_red)

        let constraint_yellow = NSLayoutConstraint.init(item: self.view, attribute: .centerX, relatedBy: .equal, toItem: _yellowView, attribute: .centerX, multiplier: 1, constant: 0)
        self.view.addConstraint(constraint_yellow)

        let constraint_yellow1 = NSLayoutConstraint.init(item: _redView, attribute: .centerX, relatedBy: .equal, toItem: _yellowView, attribute: .leading, multiplier: 0.5, constant: 0)
        self.view.addConstraint(constraint_yellow1)

        let constraint_yellow2 = NSLayoutConstraint.init(item: _blueView, attribute: .centerX, relatedBy: .equal, toItem: _yellowView, attribute: .leading, multiplier: 1.5, constant: 40)
        self.view.addConstraint(constraint_yellow2)

查看https://developer.apple.com/library/ios/documentation/UserExperience/Conceptual/AutolayoutPG/AutoLayoutbyExample/AutoLayoutbyExample.html，上面有关于解决问题的详细描述。

我为第一个项目设置了宽度值(>=宽度)和每个项目之间的最小距离(>=距离)。然后我用Ctrl拖动第二个，第三个…项连接项之间的依赖项。