我知道距离第一个答案已经有一段时间了，但我刚刚遇到了同样的问题，我想分享我的解决方案。为了子孙后代……

我在viewDidLoad上设置了视图:

- (void)viewDidLoad {

    [super viewDidLoad];

    cancelButton = [UIButton buttonWithType: UIButtonTypeRoundedRect];
    cancelButton.translatesAutoresizingMaskIntoConstraints = NO;
    [cancelButton setTitle:@"Cancel" forState:UIControlStateNormal];
    [self.view addSubview:cancelButton];

    middleButton = [UIButton buttonWithType: UIButtonTypeRoundedRect];
    middleButton.translatesAutoresizingMaskIntoConstraints = NO;
    [middleButton setTitle:@"Middle" forState:UIControlStateNormal];
    [self.view addSubview:middleButton];

    nextButton = [UIButton buttonWithType: UIButtonTypeRoundedRect];
    nextButton.translatesAutoresizingMaskIntoConstraints = NO;
    [nextButton setTitle:@"Next" forState:UIControlStateNormal];
    [self.view addSubview:nextButton];


    [self.view setNeedsUpdateConstraints];

}

然后，在updateViewConstrains上，首先删除所有约束，然后创建视图字典，然后计算视图之间使用的空间。在那之后，我只是使用视觉语言格式设置约束:

- (void)updateViewConstraints {


    [super updateViewConstraints];

    [self.view removeConstraints:self.view.constraints];

    NSDictionary *viewsDictionary = NSDictionaryOfVariableBindings(cancelButton, nextButton, middleButton);

    float distance=(self.view.bounds.size.width-cancelButton.intrinsicContentSize.width-nextButton.intrinsicContentSize.width-middleButton.intrinsicContentSize.width-20-20)/  ([viewsDictionary count]-1);  // 2 times 20 counts for the left & rigth margins
    NSNumber *distancies=[NSNumber numberWithFloat:distance];

//    NSLog(@"Distancies: %@", distancies);
//    
//    NSLog(@"View Width: %f", self.view.bounds.size.width);
//    NSLog(@"Cancel Width: %f", cancelButton.intrinsicContentSize.width);
//    NSLog(@"Middle Width: %f", middleButton.intrinsicContentSize.width);
//    NSLog(@"Next Width: %f", nextButton.intrinsicContentSize.width);



    NSArray *constraints = [NSLayoutConstraint constraintsWithVisualFormat:@"|-[cancelButton]-dis-[middleButton]-dis-[nextButton]-|"
                                                                   options:NSLayoutFormatAlignAllBaseline
                                                                   metrics:@{@"dis":distancies}
                                                                     views:viewsDictionary];


    [self.view addConstraints:constraints];



    constraints = [NSLayoutConstraint constraintsWithVisualFormat:@"V:[nextButton]-|"
                                                          options:0
                                                          metrics:nil
                                                            views:viewsDictionary];
    [self.view addConstraints:constraints];



}

这种方法的好处是你只需要做很少的数学运算。我并不是说这是完美的解决方案，但我为我试图实现的布局工作。

我希望这能有所帮助。

Swift 3版本

let _redView = UIView()
        _redView.backgroundColor = UIColor.red
        _redView.translatesAutoresizingMaskIntoConstraints = false

        let _yellowView = UIView()
        _yellowView.backgroundColor = UIColor.yellow
        _yellowView.translatesAutoresizingMaskIntoConstraints = false

        let _blueView = UIView()
        _blueView.backgroundColor = UIColor.blue
        _blueView.translatesAutoresizingMaskIntoConstraints = false

        self.view.addSubview(_redView)
        self.view.addSubview(_yellowView)
        self.view.addSubview(_blueView)

        var views = ["_redView": _redView, "_yellowView": _yellowView, "_blueView":_blueView]

        var nslayoutConstraint_H = NSLayoutConstraint.constraints(withVisualFormat: "|->=0-[_redView(40)]->=0-[_yellowView(40)]->=0-[_blueView(40)]->=0-|", options: [.alignAllTop, .alignAllBottom], metrics: nil, views: views)
        self.view.addConstraints(nslayoutConstraint_H)

        var nslayoutConstraint_V = NSLayoutConstraint.constraints(withVisualFormat: "V:[_redView(60)]", options: NSLayoutFormatOptions.init(rawValue: 0), metrics: nil, views: views)
        self.view.addConstraints(nslayoutConstraint_V)


        let constraint_red = NSLayoutConstraint.init(item: self.view, attribute: .centerY, relatedBy: .equal, toItem: _redView, attribute: .centerY, multiplier: 1, constant: 0)
        self.view.addConstraint(constraint_red)

        let constraint_yellow = NSLayoutConstraint.init(item: self.view, attribute: .centerX, relatedBy: .equal, toItem: _yellowView, attribute: .centerX, multiplier: 1, constant: 0)
        self.view.addConstraint(constraint_yellow)

        let constraint_yellow1 = NSLayoutConstraint.init(item: _redView, attribute: .centerX, relatedBy: .equal, toItem: _yellowView, attribute: .leading, multiplier: 0.5, constant: 0)
        self.view.addConstraint(constraint_yellow1)

        let constraint_yellow2 = NSLayoutConstraint.init(item: _blueView, attribute: .centerX, relatedBy: .equal, toItem: _yellowView, attribute: .leading, multiplier: 1.5, constant: 40)
        self.view.addConstraint(constraint_yellow2)

Here is a solution that will vertically center any number of subviews, even if they have unique sizes. What you want to do is make a mid-level container, center that in the superview, then put all the subviews in the container and arrange them with respect to one another. But crucially you also need to constrain them to the top and bottom of the container, so the container can be correctly sized and centered in the superview. By figuring the correct height from its subviews, the container can be vertically centered.

在本例中，self是位于所有子视图居中的父视图。

NSArray *subviews = @[ (your subviews in top-to-bottom order) ];

UIView *container = [[UIView alloc] initWithFrame:CGRectZero];
container.translatesAutoresizingMaskIntoConstraints = NO;
for (UIView *subview in subviews) {
    subview.translatesAutoresizingMaskIntoConstraints = NO;
    [container addSubview:subview];
}
[self addSubview:container];

[self addConstraint:[NSLayoutConstraint constraintWithItem:container attribute:NSLayoutAttributeLeft relatedBy:NSLayoutRelationEqual
                                                    toItem:self attribute:NSLayoutAttributeLeft multiplier:1.0f constant:0.0f]];
[self addConstraint:[NSLayoutConstraint constraintWithItem:container attribute:NSLayoutAttributeRight relatedBy:NSLayoutRelationEqual
                                                    toItem:self attribute:NSLayoutAttributeRight multiplier:1.0f constant:0.0f]];
[self addConstraint:[NSLayoutConstraint constraintWithItem:container attribute:NSLayoutAttributeCenterY relatedBy:NSLayoutRelationEqual
                                                    toItem:self attribute:NSLayoutAttributeCenterY multiplier:1.0f constant:0.0f]];

if (0 < subviews.count) {
    UIView *firstSubview = subviews[0];
    [container addConstraint:[NSLayoutConstraint constraintWithItem:firstSubview attribute:NSLayoutAttributeTop relatedBy:NSLayoutRelationEqual
                                                             toItem:container attribute:NSLayoutAttributeTop multiplier:1.0f constant:0.0f]];
    UIView *lastSubview = subviews.lastObject;
    [container addConstraint:[NSLayoutConstraint constraintWithItem:lastSubview attribute:NSLayoutAttributeBottom relatedBy:NSLayoutRelationEqual
                                                             toItem:container attribute:NSLayoutAttributeBottom multiplier:1.0f constant:0.0f]];

    UIView *subviewAbove = nil;
    for (UIView *subview in subviews) {
        [container addConstraint:[NSLayoutConstraint constraintWithItem:subview attribute:NSLayoutAttributeCenterX relatedBy:NSLayoutRelationEqual
                                                                 toItem:container attribute:NSLayoutAttributeCenterX multiplier:1.0f constant:0.0f]];
        if (subviewAbove) {
            [container addConstraint:[NSLayoutConstraint constraintWithItem:subview attribute:NSLayoutAttributeTop relatedBy:NSLayoutRelationEqual
                                                                     toItem:subviewAbove attribute:NSLayoutAttributeBottom multiplier:1.0f constant:10.0f]];
        }
        subviewAbove = subview;
    }
}

在InterfaceBuilder中解决这个问题非常简单:

设置居中标签(label2)为“水平容器中心”和“垂直容器中心”

选择居中标签和顶部标签(label1 + label2)，并为垂直间距添加两个约束。大于或等于最小间距的一个。小于或等于最大间距的一个。

中间的标签和底部的标签(label2 + label3)也是如此。

此外，您还可以添加两个约束label1 -顶部空间到SuperView和两个约束label2 -底部空间到SuperView。

结果是所有4个空格的大小变化相同。

这里还有另一个答案。我在回答一个类似的问题时看到了这个问题的链接。我没有看到任何与我类似的答案。所以我想写在这里。

  class ViewController: UIViewController {

    override func viewDidLoad() {
        super.viewDidLoad()
        view.backgroundColor = UIColor.whiteColor()
        setupViews()
    }

    var constraints: [NSLayoutConstraint] = []

    func setupViews() {

        let container1 = createButtonContainer(withButtonTitle: "Button 1")
        let container2 = createButtonContainer(withButtonTitle: "Button 2")
        let container3 = createButtonContainer(withButtonTitle: "Button 3")
        let container4 = createButtonContainer(withButtonTitle: "Button 4")

        view.addSubview(container1)
        view.addSubview(container2)
        view.addSubview(container3)
        view.addSubview(container4)

        [

            // left right alignment
            container1.leftAnchor.constraintEqualToAnchor(view.leftAnchor, constant: 20),
            container1.rightAnchor.constraintEqualToAnchor(view.rightAnchor, constant: -20),
            container2.leftAnchor.constraintEqualToAnchor(container1.leftAnchor),
            container2.rightAnchor.constraintEqualToAnchor(container1.rightAnchor),
            container3.leftAnchor.constraintEqualToAnchor(container1.leftAnchor),
            container3.rightAnchor.constraintEqualToAnchor(container1.rightAnchor),
            container4.leftAnchor.constraintEqualToAnchor(container1.leftAnchor),
            container4.rightAnchor.constraintEqualToAnchor(container1.rightAnchor),


            // place containers one after another vertically
            container1.topAnchor.constraintEqualToAnchor(view.topAnchor),
            container2.topAnchor.constraintEqualToAnchor(container1.bottomAnchor),
            container3.topAnchor.constraintEqualToAnchor(container2.bottomAnchor),
            container4.topAnchor.constraintEqualToAnchor(container3.bottomAnchor),
            container4.bottomAnchor.constraintEqualToAnchor(view.bottomAnchor),


            // container height constraints
            container2.heightAnchor.constraintEqualToAnchor(container1.heightAnchor),
            container3.heightAnchor.constraintEqualToAnchor(container1.heightAnchor),
            container4.heightAnchor.constraintEqualToAnchor(container1.heightAnchor)
            ]
            .forEach { $0.active = true }
    }


    func createButtonContainer(withButtonTitle title: String) -> UIView {
        let view = UIView(frame: .zero)
        view.translatesAutoresizingMaskIntoConstraints = false

        let button = UIButton(type: .System)
        button.translatesAutoresizingMaskIntoConstraints = false
        button.setTitle(title, forState: .Normal)
        view.addSubview(button)

        [button.centerYAnchor.constraintEqualToAnchor(view.centerYAnchor),
            button.leftAnchor.constraintEqualToAnchor(view.leftAnchor),
            button.rightAnchor.constraintEqualToAnchor(view.rightAnchor)].forEach { $0.active = true }

        return view
    }
}

同样，这也可以用iOS9 UIStackViews很容易做到。

class ViewController: UIViewController {

    override func viewDidLoad() {
        super.viewDidLoad()
        view.backgroundColor = UIColor.greenColor()
        setupViews()
    }

    var constraints: [NSLayoutConstraint] = []

    func setupViews() {

        let container1 = createButtonContainer(withButtonTitle: "Button 1")
        let container2 = createButtonContainer(withButtonTitle: "Button 2")
        let container3 = createButtonContainer(withButtonTitle: "Button 3")
        let container4 = createButtonContainer(withButtonTitle: "Button 4")

        let stackView = UIStackView(arrangedSubviews: [container1, container2, container3, container4])
        stackView.translatesAutoresizingMaskIntoConstraints = false
        stackView.axis = .Vertical
        stackView.distribution = .FillEqually
        view.addSubview(stackView)

        [stackView.topAnchor.constraintEqualToAnchor(view.topAnchor),
            stackView.bottomAnchor.constraintEqualToAnchor(view.bottomAnchor),
            stackView.leftAnchor.constraintEqualToAnchor(view.leftAnchor, constant: 20),
            stackView.rightAnchor.constraintEqualToAnchor(view.rightAnchor, constant: -20)].forEach { $0.active = true }
    }


    func createButtonContainer(withButtonTitle title: String) -> UIView {
        let button = UIButton(type: .Custom)
        button.translatesAutoresizingMaskIntoConstraints = false
        button.backgroundColor = UIColor.redColor()
        button.setTitleColor(UIColor.whiteColor(), forState: .Normal)
        button.setTitle(title, forState: .Normal)
        let buttonContainer = UIStackView(arrangedSubviews: [button])
        buttonContainer.distribution = .EqualCentering
        buttonContainer.alignment = .Center
        buttonContainer.translatesAutoresizingMaskIntoConstraints = false
        return buttonContainer
    }
}

注意，这与上面的方法完全相同。它添加了四个容器视图，这些视图都是均等填充的，每个堆栈视图都添加了一个视图，并在中间对齐。但是，这个版本的UIStackView减少了一些代码，看起来不错。

基于Ben Dolman的回答，这将更均匀地分配视图(使用填充等):

+(NSArray *)constraintsForEvenDistributionOfItems:(NSArray *)views
                           relativeToCenterOfItem:(id)toView vertically:(BOOL)vertically
{
    NSMutableArray *constraints = [NSMutableArray new];
    NSLayoutAttribute attr = vertically ? NSLayoutAttributeCenterY : NSLayoutAttributeCenterX;

    CGFloat min = 0.25;
    CGFloat max = 1.75;
    CGFloat d = (max-min) / ([views count] - 1);
    for (NSUInteger i = 0; i < [views count]; i++) {
        id view = views[i];
        CGFloat multiplier = i * d + min;
        NSLayoutConstraint *constraint = [NSLayoutConstraint constraintWithItem:view
                                                                      attribute:attr
                                                                      relatedBy:NSLayoutRelationEqual
                                                                         toItem:toView
                                                                      attribute:attr
                                                                     multiplier:multiplier
                                                                       constant:0];
        [constraints addObject:constraint];
    }

    return constraints;
}